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  • 1,2,4-Triazole is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms.
  • 1,2,4-Triazole is a basic aromatic heterocycle. 1,2,4-Triazole derivatives find use in a wide variety of applications, most notably as antifungals such as fluconazole and itraconazole.
  • 1,2,4-Triazoles can be prepared using the Einhorn-Brunner reaction or the Pellizzari reaction.
  • 1,2,4-Triazole, triazole alanine, triazole acetic acid, triazole pyruvic acid and triazole lactic acid are the common metabolites derived from triazole-containing fungicides that act by inhibiting sterol synthesis.
  • 1,2,4-Triazole, triazole alanine and triazole acetic acid are the
    commonly used names for IUPAC nomenclatures 1H-1,2,4-triazole, 1,2,4-triazolyl-3-alanine, and 1H-1,2,4-triazol-l-ylacetic acid ,respectively.
  • These three metabolites commonly occur as plant or soil metabolites and are collectively known as the “triazole derivative metabolites”.
  • Triazole alanine and triazole acetic acid residues are primarily associated with plant commodities, while 1,2,4-triazole is mainly associated with animal commodities, lesser amounts of this compound being found in plant commodities.
  • The toxicological database for 1,2,4-triazole was sufficient for
    the evaluation of this compound, while the toxicological databases for triazole alanine and triazole acetic acid were more limited.
  • The inhibition of Salmonella typhimurium by 1,2,4-triazole appears to be mediated through an effect on L-cysteine biosynthesis.
  • 0-Acetylserine sulfhydrylase A, the final enzyme in the L-cysteine
    biosynthetic pathway, was found to catalyze a reaction between 0-acetyl-L-serine and 1,2,4triazole, giving 1,2,4-triazole-1-alanine as a product.
  • In wild type S. typhimurium grown on 4 mM I,2,4-triazole, 97% of the total 0-acetyl-L-serine synthesized in uivo is incorporated into 1,2,4-triazole-lalanine.
  • 1,2,4-Triazole also significantly lowers the levels of several of the enzymes necessary for sulfate reduction.
  • In vitro studies, using purified preparations of 0-acetylserine sulfhydrylase A, revealed greater losses of triazolylase activity than sulfhydrylase activity in the enzymes from both cysK mutants.
  • Resistance to 1,2,4-triazole apparently can arise from mutations leading to a preferential loss of triazolylase activity or from mutations which diminish both activities to the extent that high concentrations of 0-acetyl-L-serine and sulfide accumulate behind the sulfhydrylase reaction.
  • Triazole fungicide metabolites.
  • One pot procedure for trisubstituted 1,2,4-trizoles.


  • Use of 3-Amino-l,2,4-triazole To Reduce Body Catalase
    Activity in Cancer Studies.


  • Cayman chemical product information sheet.
  • Product information for 3-amino-1,2,4-triazol.
  • Paclobutrazol data sheet.
  • Rebetol product sheet.


  • Design, synthesis and evaluation of 1,2,4-triazole derivatives as antifungal.
  • An Improved Synthesis of 1,2,4-Triazoles using Ag2CO3.
  • Synthesis and insecticidal activity of 1,2,4-triazole derivatives.
  • Synthesis of 1,2,4-Triazole-Functionalized Solid Support and Its Use in the Solid-Phase
    Synthesis of Trisubstituted
  • New Regioselective Synthesis and Biological Activity of Substituted 1H-[1,2,4]Triazolo[3,4-c][1,2,4]triazoles.
  • Synthesis of some Antifungal and Anti-tubercular 1, 2, 4-Triazole Analogues.
  • Electronic Supporting Information Hypergolic Ionic Liquids to Mill, Passivate, Suspend, and Ignite Boron Nanoparticles.
  • Systematic Method of 1,2,4-Triazole.


  • Pesticide residues in food 2008.
  • 1H-1,2,4-triazole.
  • Structural and Theoretical Investigations of 3,4,5-Triamino-1,2,4-Triazolium Salts.
  • Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebuconazole.
  • 1-(2',4',6'-Trinitrophenyl)imidazoles and -1,2,4-triazoles as Energetic Materials.
  • Ionic Liquids as Energetic Materials.
  • Method of obtaining derivatives of 3,5-dinitro-1,2,4-tryazole.
  • Triazaboles and Related Triazole Derivatives of Boron.


  • One pot synthesis of 1,2,4-triazoles.
  • Method of producing 1,2,4-triazole.
  • Preparation of 3, 5-dinitro-1, 2, 4-triazole.
  • 5-oxo-3-nitro-1,2,4-triazole in gunpowder and propellant compositions.
  • Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand.

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  • Suppliers of 1,2,4-triazole.
  • Manufacturers of 1,2,4-triazole.
  • Selling leads of 1,2,4-triazole.
  • Suppliers of China.
  • Exporters of 1,2,4-triazole.
  • List of 1,2,4-triazole suppliers
  • Suppliers of china1.

Company profiles

  • Company from Mumbai.
  • Company from Gujarat
  • Company from Zhuzhou.


  • Consultancy from London.
  • Consultancy from Gujarat.
  • Consultancy from Shanghai.
  • Consultancy from UK.
  • Online consultancy


  • Safety data sheet for 1,2,4-triazole-3-carboxamide.
  • Coppeready data sheet.
  • 1,2,4-triazole data sheet.
  • Safety data sheet for 1,2,4-triazole.
  • 3-mercapto-1,2,4-triazole.
  • 1,2,4-triazole pure data sheet.
  • 1,2,4-Triazole, sodium derivative data sheet.


  • 5,5´-Dinitrimino-3,3´-methylene-1H-1,2,4-bistriazole a Metal Free Primary Explosive Combining Excellent Thermal Stability and High Performance.
  • Acidic properties of some 1,2,4-triazole derivatives in non-aqueous media.
  • Asian Journal of Biochemical and Pharmaceutical Research:A review on 1,2,4-triazoles.
  • Synthesis, characterization and anticancer activity of 1,2,4-Triazolo [3,4-b]-1,3,4-thiadiazoles on Hep G2 cell lines.


  • Incorporation of 1,2,4-triazole-3-alanine into a mutant of phage
    lambda lysozyme containing a single histidine.
  • Design and synthesis of new 1,2,4-triazole derivatives containing morpholine moiety as antimicrobial agents.
  • Novel 1,2,4-triazole and imidazole derivatives of L-ascorbic and
    imino-ascorbic acid: Synthesis, anti-HCV and antitumor activity evaluations.
  • Chiral 1,2,4-triazole derivatives as potential synthetic intermediates.
  • Qsar study 1,2,4-triazoles using several physicochemical descriptors.
  • Quantum chemical studies on tautomerism and basicity
    behavior of some 1,2,4-triazole derivatives.
  • Silver complexes of 1,2,4-triazole derived N-heterocyclic carbenes:
    Synthesis, structure and reactivity studies.
  • Studies on the Mechanism of Inhibition of Salmonella
    typhimurium by 1,2,4-Triazole

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