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Information @ a Glance

Contents on the CD Rom

  • Captafol is a fungicide. It is used to control almost all fungal diseases of plants except powdery mildews.
  • Captafol is a broad-spectrum protective contact fungicide belonging to the sulfanilamide group.
  • Captafol is an alkylating agent and has produced genotoxic effects in a variety of systems.
  • Captafol is used widely to control diseases on apples, citrus fruits, tomatoes, cranberries, potatoes, coffee, pineapples, peanuts, onion,
    stone fruits, cucumbers, blueberries, prunes, watermelons, sweet corn, wheat, barley, oilseed rape, leeks, strawberries, cotton, peanuts and rice.
  • Captafol is prepared by the reaction of tetrahydrophthalimide and 1,1,2,2-tetrachloroethylsulfenyl chloride in the presence of aqueous  sodium hydroxide
  • A simple and rapid colorimetric method for the microdetermination of captafol (difolatan), based on its reaction with a  dithiocarbamate, has been developed. The bright yellow colour which develops instantaneously on mixing the fungicide with the
    reagent is stable for at least 12 h. The method has been successfully adapted to the determination of captafol in its formulated products
    and residues on grains and apples.
  • In vitro effects of fungicide captafol on the production of IL-1 and IL-2 was studied in avian splenic mononuclear cells.
  • Captafol was tested for carcinogenicity in feeding studies in CD-1 mice, B6C3F1 mice, Crl:CD rats, and F344 rats.
  • Several registered fungicides evaluated over a 7-yearperiod in the southern San Joaquin Valley controlled the disease on fruit. Captan, captafol, and ziram preceded by dormant copper provided the most consistent control.
  • A method has been developed for the analysis of seven fungicides in environmental waters, using solid-phase microextraction (SPME).
    The analyzed compounds dicloran, chlorothalonil, vinclozolin, dichlofluanid, captan, folpet and captafol belong to different
    classes of chemical compound (chloroanilines, sulphamides, phthalimides and oxazolidines) and are used mainly in agriculture and as antifouling paints.
General Information
  • Captafol
  • Captafol (Difolatan) Chemical Fact Sheet
  • Captafol - Pesticide Information Profile
  • Carcinogens Background Document for Captafol


  • Consultant from USA
  • Consultant from Washington

Production Process

  • Analytical Challenges for monitoring of phthalimide pesticides in fruits and vegetables and some solutions
  • Compound-independant elemental quantitation of pesticides by gas chromatography with atomic emission detection(GC/AED)
  • Pesticides manufacturing process
  • Captafol Processing
  • New Developments in LC/MS/MS,
    GC/MS, GC/MS/MS Methods for the Analysis of Pesticides and their Degradation Products
  • Multiresidue Analysis of 50 Pesticides in Grape, Pomegranate, and Mango by Gas Chromatography-Ion Trap Mass Spectrometry
  • Captafol Production


  • Effect of fungicides on shot hole disease of almonds
  • Evauation of Metalaxyl and Captafol soil drenches, composted hardwood bark soil amendments, and graft union placement on control of apple collar rot
  • Field efficacy of reduced rates of various 50% copper formulations against coffee berry disease in kenya
  • Fungicidal control of bunch grape diseases in florida
  • Bioefficacy of Pyraclostrobin 25%EC Against Early Blight of Tomato


  • Effects of fungicides on seed borne pathogen of groundnut
  • Control of Fusarium Crown and Root Rot of Greenhouse Tomatoes by Inhibiting Recolonization of Steam-Disinfested Soil with a Captafol Drench
  • Fungicides - Gas Chromatography
  • Determination of fungicides in natural waters using solid-phase microextraction and gas chromatography coupled with electron-capture and mass spectrometric detection
  • Advances in the analysis of pesticides typically analysed by single-residue methods
  • Controlof anthracnose of avocados: Techniques to evaluate fungicides
Company Profiles
  • Company from California
  • Company from India
  • Company from Pennsylvania
  • Company from USA


  • Fungicidal Active Compound Combinations
  • Roughage animal feed
  • Fungicidal Composition
  • Synergistic fungicidal mixture of captafol and thiabendazol

Uses & Functions

  • Control of Strawberry Anthracnose with Captafol
  • Control of mango anthracnose with foliar sprays
  • Influence of Selected Protectant Fungicides and Host Resistance on Simple and Complex Potato Late Blight Forecasts
  • Allergic Contact and Photoallergic Contact Dermatitis to Plant and Pesticide Allergens
  • Pre-Harvest chemical control of anthracnose and sooty blotch
  • Effect of Fertilizers, fungicides and herbicides on the fate of c-parathion and c- fonofos in soils and crops

Report & Regulatory Act

  • Consideration of elaboration of MRLS for spices - Codex committee on pesticide residue
  • Captafol/o-Nitrotoluene Expert Panel Report
  • Reasonably anticipated to be a human carcinogen - Captafol
  • FAO Specifications for plant protection products - Captafol
  • Restricted Use Pesticides
  • Regulatory Tracking Summary - Captafol


  • Hazard Alert - Captafol
  • Decision guidance Documents - Captafol
  • Occupational safety and health guideline for Captafol
  • EPA act of  Benzaldehyde, Captafol, Hexaconazole, Paraformaldehyde,
    Sodium dimethyldithiocarbamate, and Tetradifon; Tolerance Actions


  • Captafol manufacturer & suppliers
  • UK Suppliers of Captafol


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