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Information @ a Glance

Contents on the CD Rom

  • Validamycin is a agricultural antibiotic. All its molecules contain glucose.

  • Validamycin solution is brownish transparent liquid, and the technical product is a color-less and odorless hygroscopic powder, soluble in water, dimethyl formamide, insoluble in ethyl acetate, ethyl ether and petroleum ether.

  • Validamycin is a kind of agricultural antibiotic with good control on disease of fungi such as sheath blight of rice, wheat and corn without pollution to environment.

  • Validamycin A , a commercially used agricultural antifungal antibiotic, is a microbialderived pseudotrisaccharide, which contains a core aminocyclitol moiety, validoxylamine A , and glucose.

  • Validamycin is a water soluble antibiotics produced by Strep. Hygroscopicus Var. Jinggangensis Yen, which consists of six components named A, B, C, D, E, F respectively. Validamycin A is the major active ingredient.

  • Validamycin A is a member of microbial-derived C7N-aminocyclitol family of natural products that is widely used as crop protectant and the precursor of the antidiabetic drug voglibose.

  • A gene cluster responsible for the biosynthesis of validamycin, an aminocyclitol antibiotic widely used as a
    control agent for sheath blight disease of rice plants, was identified from Streptomyces hygroscopicus subsp.
    jinggangensis 5008 using heterologous probe acbC, a gene involved in the cyclization of D-sedoheptulose
    7-phosphate to 2-epi-5-epi-valiolone of the acarbose biosynthetic gene cluster originated from Actinoplanes sp.strain SE50/110.

  • ValG is a glycosyltransferase (GT) that is responsible for the glucosylation of validoxylamine A to validamycin A.

  • A 45 kb DNA sequencing analysis from Streptomyces
    hygroscopicus 5008 involved in validamycin A (VALA)
    biosynthesis revealed 16 structural genes, 2 regulatory
    genes, 5 genes related transport, transposition /integration or tellurium resistance; another 4 genes had no obvious identity.

  • China plays a major role in antibiotics production. Antibiotics of industrial, agricultural and medicinal significance like erythromycin, avermectin and validamycin are produced in vast amounts every year.

General Information
  • Validamycin Data Sheet
  • Validamycin Chemical Profiles
  • Validamycin Pesticide Information

Process & Production

  • Determination of the antibiotic fungicide validamycin A in formulated products by micellar electrokinetic chromatorphy
  • Gene Cluster Responsible for Validamycin Biosynthesis in
    Streptomyces hygroscopicus subsp. jinggangensis 5008
  • Nucleotidylation of Unsaturated Carbasugar in Validamycin Biosynthesis
  • ValC, a New Type of C7-Cyclitol Kinase Involved in the Biosynthesis of the Antifungal Agent Validamycin A
  • Production of Validamycin from crude substrates by streptomyces hygroscopicus in an external-loop airlift bioreactor with a low height-to-diameter ratio


  • Trehalase activity in plant tissue cultures
  • Foliar Spray of Validamycin A
    or Validoxylamine A Controls Tomato Fusarium Wilt
  • Study on optimal production of 3-ketovalidoxylamine A
    C-N lyase and glucoside 3-dehydrogenase by a newly
    isolated Stenotrophomonas maltrophilia


  • Catalytic Analysis of the Validamycin Glycosyltransferase (ValG) and Enzymatic Production of 4″-epi-Validamycin A
  • Functional Analysis of the Validamycin Biosynthetic Gene Cluster and Engineered
    Production of Validoxylamine A
  • Synthetic studies on the validamycins. i. Synthesis of beta-D-glucopyranosylvalidamine: 1l-2-o- (beta-D-glucopyranosylvalidamine)-1,3,4/2,6)-4-amino-6-hyroxylmethyl-1,2,3-cyclohexanetriol


  • Antibiotic biosynthetic pathways and pathway engineering—a growing research field in China
  • HPLC analysis of trehalose and other soluble carbohydrates from the leaf tissue of indica and japonica rice varieties
  • Quantitative analysis of Valienamine in the microbial degradation of Validamycin A after derivatization with p-nitrofluorobenzene by reversed-phase high-performance liquid chromatography
Company Profiles & Plant
  • Company from Delhi
  • Company from Hong Kong
  • Plant from Orissa
  • Consultant from China
  • Consultant from Delhi
  • Consultant from USA
  • Consultant from Oregon
  • Global Consultant


  • Validamycin A sc 281183
  • Validamycin A


  • Antibiotic compositions containing validamycin compounds
  • Validamycin C, D, E and F antibiotics
  •  Method for Producing a Validamycin A analog and uses therof
  • Valiolone, a method of preparing it, and its use to prepare acarbose and voglibose
  • Fungicidal Mixtures Of Amidinylphenyl Compounds
  • Valiolamine derivatives and production thereof


  • Effects of trehalose on gene expression in Arabidopsis thaliana seedlings: a genome-wide analysis
  • Effect of Validamycin A on the Inositol Content and Branching of Rhizoctonia cerealis and Other Fungi
  • Inhibition of trehalose breakdown increases new carbon partitioning into cellulosic biomass in Nicotiana tabacum
  • Physiological implications of trehalase from Phaseolus vulgaris root nodules: partial purification and characterization
  • Effect of Validamycin A on the Production of Cellulase, Xylanase and Polygalacturonase by Rhizoctonia solani


  • Validamycin Selling leads
  • Validamycin Supplier List
  • Validamycin Exporters
  • Validamycin Manufacturer & Suppliers
  • Validamycin Sellers

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