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Project Information Profile at a glance

  • Griffonia simplicifolia is a woody climbing shrub native to West Africa and Central Africa. It grows to about 3 m, and bears greenish flowers followed by black pods.
  • The seeds of the plant are used as a herbal supplement for their 5-Hydroxytryptophan content. 5-Hydroxytryptophan may be extracted from seeds as a supplement which as a serotonin precursor is beneficial in serotonin deficiency. Ongoing research suggests that 5-Hydroxytryptophan may also be beneficial in mood disorders including mild to moderate clinical depression and sleeping disorders.
  • Children with sleep disorder-related headaches seem to respond to 5-HTP treatment. It alleviates the effects of a variety of conditions, including depression, anxiety, insomnia and obesity.
  • 5-hydroxytryptophan is a more potent in vitro hydroxyl radical scavenger than melatonin or vitamin C.
  • 5HTP induced increase in salivary cortisol in panic disorder patients and healthy volunteers.
  • Effect of orally administered L-tryptophan on serotonin, melatonin, and the innate immune response in the rat.
  • For better sleep, consider Good Night Rx. 5HTP is not consistently effective when it comes to sleep, although using a lower dose of 10 to 30 mg may be tried one to three hours before bed.
  • 5-HTP should not be used in patients currently being treated or who have recently been treated with
    an SSRI antidepressant.

 Content Headlines on CD ROM

 Growth and Cultivation
  • Griffonia simplicifolia
  • Griffonia Baillon
  • Griffonia Seed- Active Constituents
  • 5-HTP Monograph
  • Medicinal Plants Cultivation-Ghana
  • Medicinal Plant Harvesting-Africa
  • Griffonia Seed Extract (5HTP)

Products and Specifications

  • D. Plantes Catalogue- 2004
  • Colloidal Gold Catalogue
  • Selekta- Griffonia
  • HTP Complex
  • 5-HTP- Specifications
  • L-5-HTP- Specifications
  • Griffonia (Bandeiraea) simplicifolia GS I-B4
  • SleepRite
  • Physician Formulas

Binding Specificity and Chromatography Charts

  • Isolectins I-A and I-B of Griffonia (Bandeiraea) Simplicifolia
  • Purification and Characterization of Griffonia simplicifolia Leaf Lectins
  • Lectins from Griffonia Simplicifolia Seeds
  • Carbohydrate Binding of GSII
  • Glycoprotein Receptor Reactive with Griffonia simplicifolia
  • Xenograft Antigen Bound to Griffonia simplicifolia Isolectin
  • IB4 HRP-Conjugate Protocol
  • Spectrophotometric Estimation
  • Microvessel Changes in Hypertension Measured by Griffonia simplicifolia I Lectin
  • Lectin from Bandeiraea Simplicifolia Seeds- Chromatography Charts
  • 5-HTP Proposed Uses
  • Serotain
  • 5-Hydroxytryptophan Infusion Enhances Glucose Disposal in Conscious Dogs
  • Antioxidant and Anti-Apoptotic Principle
  • 5-Hydroxy-L-tryptophan Suppresses Food Intake  and Stressed Rats
  • 5-HTP plus SSRIs for Interferon-Induced Depression

Market Reports and Pricing

  • NRC
  • Global Market for Herbal Products and Pertinent Trade Issues
  • Tapping the Green Market
  • Truth Trade Technology
  • VitaFoods 2006
  • African Herbal Industry
  • IB4 Pricing
  • Time Laboratories Price List

Manufacturers and Suppliers

  • Raw Material Suppliers
  • L-5-HTP Manufacturers
  • 5-HTP Product Suppliers
  • Griffonia -Trade Leads
  • Griffonia Seed  Extract Exporters


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Primary Information Services
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Ullagaram, Chennai - 600091, India.
 Phone: 91 44 22421080 
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Mobile numbers:9940043898, 9444008898  Fax : 91 44 22423753