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Contents on the CD Rom

  • Colchicum plant has a large, ovate, solid, fleshy corm (tuber, according to some authors). The leaves are dark-green, very smooth, obtuse, 
    above a foot long, 1 1/2 inches broad, keeled, and produced in the spring along with the capsules. The flowers are several, radical, leafless, 
    and bright purple, with a long, white tube appearing in the autumn without the leaves.
  • Colchicum root is About 25 Mm. (1 inch) long, ovoid, flattish, and with a groove on one side; externally brownish and wrinkled; internally white and solid; often in transverse slices, reniform in shape, and, breaking with a short, mealy fracture; inodorous; taste sweetish, bitter, and somewhat acrid. Colchicum seed is Subglobular, about 2 Mm. ( 1/12 inch) thick, very slightly pointed at the hilum; reddish-brown, finely pitted, internally whitish; very hard and tough; inodorous; taste bitter and somewhat acrid.
  • Gloriosa superba L. is a semi-woody herbaceous branched climber, reaching approximately 5 meters in height. It is also planted outdoors in 
    the southern United States. In cool temperate countries, it is treated as a greenhouse or conservatory plant. In Bangladesh the plant is naturally found to grow in Sal Forests of Dhaka and Gazipur districts. G. superba is considered to be a herbaceous plant, little attention is given towards its propagation and culture. It is commonly grown from seeds and tubers.
  • Three Different Methods for extraction of Colchicine have been studied, and it was found that extraction with petroleum ether and chloroform is the best and most reliable method. Colchicine is readily converted into the corresponding hydroxymethylene derivative, colchiceine, by hydrolysis of the methoxymethylene group in dilute acid solution. The solution containing colchicine and colchiceine is extracted by shaking with three separate lots of 3 ml. chloroform.
  • Wash-out of joints with colchicine and diclofenac sodium significantly inhibit the increased mediator activities. Both drugs also stimulate the recovery of the degenerative changes. This effect of colchicine may be due to the inhibition of leukocyte migration, glycoprotein production and secretion in granulocytes. It has been shown that parenteral injection of colchicine inhibits LTB4 a real mediator of vertebral disc diseases.
  • Rapid toxicity technologies use various biological organisms and chemical reactions to indicate the presence of toxic contaminants. The toxic 
    contaminants are indicated by a change or appearance of color or a change in intensity. As part of this verification test, ToxScreen-II was 
    subjected to various concentrations of contaminants such as industrial chemicals, pesticides, rodenticides, pharmaceuticals, nerve agents, and biological toxins.
  • A subsequent review of medical records revealed that a third death from colchicine toxicity in a patient treated at the Oregon clinic also 
    occurred in March and likely was associated with the same compounding error. These deaths highlight the potential risk from use of IV 
    colchicine for back pain and the possibly fatal consequences of measuring errors in compounding pharmacy products. 
  • World demand for colchicine is still appreciably high today for the treatment of gout and it is sourced as a raw material for the manufacture 
    of a drug widely used in Europe for the treatment of spasticity and muscular contractures. 
  • Colchicine have been used as a probe to compare microtubules of PCI2 cells grown in the absence and in the presence of NGF. The results of 
    this comparison demonstrate that microtubules of long-term NGF-treated cells (neurite-bearing) are much less susceptible to disruption by 
    colchicine than are microtubules of cells grown in the absence of NGF (nonneurite-bearing).
  • Colchicine is Food and Drug Administration (FDA)-approved for the treatment of gout and also for familial Mediterranean fever, secondary amyloidosis(AA), and scleroderma. Colchicine poisoning resembles arsenic poisoning; the symptoms  include burning in the mouth and throat, diarrhea, stomach pain, vomiting, and kidney failure.
  • Colchicine Information
  • Pharmacology of Colchicine
  • Colchicine Drug Information
  • Colchicine
  • Colchicine Product Information
  • Colchicine

Plant Growth  and General Information

  • Gloriosa superba Linn
  • Climbing Lily
  • Gloriosa superba L
  • Glory lily Coastal Curse
  • Colchicum
  • Significance of sequential opening of flowers in Gloriosa superba L
  • Micropropagation of Gloriosa superba L. Through High Frequency Shoot Proliferation
Processing and Technology
  • Phytochemistry of Alkaloids
  • The Conversion of Colchicine into Colchiceine
  • Estimation of Colchicine in Six Different Species of Gloriosa Grown in Vitro
  • Techniques in Karyology: The Bone Marrow Extraction Method
  • Rapid Toxicity Testing System

Company Profiles

  • Company in India
  • Company at Calcutta, India
  • International Pharmaceutical Company
  • Company in Germany
  • Company at Mumbai, India
  • Manufacturer of Fine Chemicals
  • Consultant in Northern California
  • Expert in polymer synthesis, property design, degradation, flammability
  • Consultant in Cambridge, MA
  • Rapid City Journal Expert
  • Antiproliferative Colchicine Compositions and Uses thereof
  • Colchicine Derivatives, Process for Preparing them, Products obtained therefrom and Use thereof
  • Process for Extracting Compounds from Plants
  • Method of Enhancing And/Or Prolonging Expression of Gene Introduced into a cell Using Colchicine
  • Colchicine Ophthalmic Composition and Method of Use
  • Process for the Biotransformation of Colchicinoid Compounds into the Corresponding 3-glycosyl Derivatives
  • Prolonged Local Anesthesia with Colchicine
  • Use of Colchicine for the Control of Retroviruses


  • Effect of Colchicine on the Antibody Response
  • Chemical Cross-Linking of Proteins of Semliki Forest Virus
  • The Effect of Colchicine on Ocular Growth and Emmetropization
  • Effects of cytochalasins B and D and colchicine on migration of the corneal epithelium 
  • Effect of Colchicine on Iron Transport during Stages of Maturation and Enamel Pigmentation in Rat Incisor Enamel
  • The Mechanism of Action of Colchicine
  • Paradoxical Effects of Colchicine on the activation of Human Neutrophils by Chemotactic Factors and inflammatory Microcystals


  • An Experimental System to Study Phagocytosis
  • Broadening the genetic base, testing genotypes and developing breeding methods
  • From Organelle to Protein Gel: A 6-Wk Laboratory Project on Flagellar Proteins
  • Development of an internationally competitive saffron industry
  • A Study of the Genetic Improvement of Quaking and Bigtooth Aspen by Selection, Hybridization and the Exploitation of Polyploidy
  • Colchicine for alcoholic and non-alcoholic liver fibrosis and cirrhosis
  • A Convergent Total Synthesis of (&)-Colchicine and ( f )- Desacetamidoisocolchicine
  • Total Synthesis of Colchicine in Comparison
  • Total Syntheses of Colchicine
  • Radioimmunoassay of Colchicine
  • Colchicine-Induced Tetraploidy and Changes in Allele Frequencies in Colchicine-Treated Populations of Diploids Assessed with RAPD Markers in Gossypium arboreum


  • Colchicine Use in Children and Adolescents With Familial Mediterranean Fever
  • Evidence that Axoplasmic Transport of Trophic Factors is involved in the Regulation of Peripheral nerve fields in Salmanders
  • Occurrence of diploid and polyploid microspores in Sorghum bicolor (Poaceae) is the result of cytomixis
  • Colchicine Is a Competitive Antagonist at Human Recombinant g-Aminobutyric AcidA Receptors
  • Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo
  • Interest of colchicine for the treatment of cystic fibrosis patients
  • The Use of Colchicine in Arthroscopic Wash-out Fluid in Early Degenerative Arthritis of the Rabbit Knee Joint


  • Acute Plant Poisoning and Antitoxin Antibodies
  • Fatal poisoning with Colchicum autumnale
  • Poisoning by Glory Lily
  • Colchicine Side Effects & Drug Interactions
  • Colchicine Treatment and Toxicity
  • Clinical Effects
Products and Material Safety Data Sheet
  • Ayurveda and natural products drug discovery
  • Colchicine Tablets
  • Colchicine
  • USB Corporation- Colchicine
  • Colchicine 97%
  • Safety data for colchicine
  • Colchicine ~95% (HPLC), powder
  • Changes in the Colchicine Susceptibility of Microtubules Associated with Neurite Outgrowth    
  • Entrepreneurship Development through Medicinal and Aromatic Plants in North East India
  • Deaths from Intravenous Colchicine Resulting from a Compounding Pharmacy Error
  • Colon cancer: Colchicine treatment possibilities
  • In Vitro Delivery of Nano- and Micro-Particles to Human Retinal Pigment Epithelial (ARPE-19) Cells
  • Regional Research Laboratory Report
  • ISMP 2007 survey on HIGH-ALERT medications
Suppliers and Buyers
  • Colchicine Suppliers
  • Colchicine Producer and Manufacturer
  • Colchicine Selling Leads
  • Colchicine Exporters
  • Colchicine Manufacturers & Suppliers
  • Kumar World Trade
  • Manufacturers and Suppliers of Colchicine 
  • Exporters of Colchicine
  • Colchicine Buyers List
Gloriosa superba Suppliers
  • Nath International
  • Gloriosa superba Manufacturers & Suppliers
  • Cultivators and Exporters of Gloriosa superba 

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