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Contents on the CD Rom

  • Ketamine hydrochloride, or "Special K," is a powerful hallucinogen widely used as an animal tranquilizer by veterinarians. Users sometimes call the high caused by Special K, "K hole," and describe profound hallucinations that include visual distortions and a lost sense of time, sense, and identity.
  • Ketamine is a dissociative anesthetic developed in 1963 to replace PCP and currently used in human anesthesia and veterinary medicine. Much of the ketamine sold on the street has been diverted from veterinarians' offices.
  • Ketamine's chemical structure and mechanism of action are similar to those of PCP Ketamine hydrochloride ("Special K" or "K") was originally created for use as a human anaesthetic.
  • Ketamine belongs to a class of drugs called "dissociative anaesthetics," which separate perception from sensation. Other drugs in this category include PCP, DXM and nitrous oxide (laughing gas).
  • Product resulting from grignard reaction involving o-chlorobenzonitrile &  bromocyclopentane is treated in presence of strong alkali to form epoxy cmpd. Reaction of this with methylamine yields imine which rearranges on heating in presence of hcl.
  • Use of ketamine to treat severe cancer pain. The physiologic effects of the use of Telazol-ketamine-xylazine on feral cats in a large-volume spay and neuter clinic.
  • The use of ketamine hydrochloride as an anesthetic for raccoons. Ketamine continues to be used extensively in children and for short-term anaesthesia and analgesia in-patients with burns.
  • In veterinary anesthesia, ketamine is often used for its anaesthetic and analgesic effects on cats, dogs, rabbits, rats, and other small animals. Veterinarians often use ketamine with sedative drugs to produce balanced anaesthesia and analgesia, and as a constant rate infusion to help prevent pain wind-up. Ketamine is used to manage pain among large animals, though it has less effect on bovines.
  • The effect of ketamine on the respiratory and circulatory systems is different from that of other anaesthetics. When used at anaesthetic doses, it will usually stimulate rather than depress the circulatory system. It is sometimes possible to perform ketamine anaesthesia without protective measures to the airways.
  • Ketamine is sold in either powdered or liquid form. In powdered form, its appearance is similar to that of pharmaceutical grade cocaine and can be insufflated (referred to as a "SPECIAL K"), injected, or placed in beverages.
  • There are three main types of ketamine infusion techniques currently being performed on RSD / CRPS patients for the relief of their pain and allodynia symptoms.
  • Propofol-fentanyl-midazolam combination is found to be far superior to propofol-pethidine-midazolam and ketamine-midazolam combinations in respect to haemodynamic stability, oxygenation, shifting to PACU, incidence of complications and discharge readiness.
  • Ketamine has been recommended as an alternative to thiopental sodium for the induction of general anesthesia in patients undergoing elective cesarean section. Compared to thiopental sodium induction, ketamine induction yields a significantly lower intraoperative maternal awareness and better neonatal outcome.
  • According to the survey , 1329 users (14.8% of respondents) had tried ketamine, the vast majority on an experimental or occasional basis, with 279 individuals (3%) claiming to use occasionally or more often. The proportion of users each year is relatively stable between a low of 13.0%, and a high of 18.4% in the smaller in the corresponding year. Similarly current use remains relatively stable at 2-3%.
General
  • Ketamine introduction
  • Drug Description
  • Club Drugs
  • Ketamine-Drug Information
  • Ketamine
  • Drug Info

Process

  • Production Process and Analysis
  • Stimulated Moving Bed Adsorption for Seperation of Racemic Mixtures
  • Synthesis
  • Synthesis of Ketamine
  • Synthesis of Ketamine-Complete
  • Total Synthesis of Ketamine

Company Profiles

  • Company in Kolkata
  • Company in China
  • Company in Taiyuan
  • Company in Cambridge, Massachusetts

Consultants

  • Consultant in Greece
  • Consultant in Barrington, Illinois
  • Consultant in Arizona
  • Consultant in Allen's Nek

Production

  • Ketamine
  • The Potential Expansion of  Methamphetamine Production and Distribution in Canada
  • Club Drugs: An Overview
  • The Development of Single Enantiometer drugs from racemates
  • Singapore: History of Illicit Drug

Properties and Functions

  • Analgesic effect of caudal epidural ketamine in cattle
  • Effects of Xylazine-Diazepam-Ketamine and Xylazine-Tiletamine-Zolazepam Anesthesia on Some Coagulation Parameters in Horses
  • Ketamine Inhibits Inositol 1,4,5-Trisphosphate Production Depending on the Extracellular Ca21 Concentration in Neonatal Rat Cardiomyocytes
  • Optimization of a simple method for the chiral separation of methamphetamine and related compounds in clandestine tablets
  • Effects of Ketamine and Midazolam on Morphine induced dependence and Tolerance in Mice
  • Ketamine Modulates the Stimulated Adhesion Molecule Expression on Human Neutrophils In Vitro
  • Physical and psychological effects
  • Effects on Human Performance and Behavior
  • Ketamine suppresses intestinal NF-kappa B activation and proinflammatory cytokine in endotoxic rats
  • Effects of ketamine on proinfl ammatory cytokines and nuclear factor kappaB in polymicrobial sepsis rats
  • Actions of Ketamine on the Body

Techniques

  • Ketamine Infusion- Three Techniques
  • Comparison of Various techniques sedation techniques for transvaginal oocyte retrieval in a daycare setup
  • Low cost techniques
  • Observations on the use of medetomidine/ketamine and its reversal with atipamezole for chemical restraint in the mouse
  • A Comparison of Propofol and Ketamine as Induction Agents for Cesarean Section

Patent

  • Process for the preparation of ketamine ointment
  • Ketamine analogues for the treatment of thrombocytopenia
  • Use of ketamine for the manufacturing of medicaments for prevention or reduction of the effects of stroke in a subject having increased risk for stroke
  • Ketamine and n-butyl-p-aminobezoate in PLO
Application
  • Ketamine in the Treatment of Refractory Cancer Pain
  • The physiologic effects of the use of Telazol-ketamine-xylazine on feral cats in a large-volume spay and neuter clinic
  • Ketamine: the introduction and clinical use
  • The Use of Ketamine Hydrochloride as an Anesthetic for Raccoons
  • Therapeutic Uses of Ketamine
  • Ketamine Special K Drug Use teens
  • Uses of Ketamine

Product Information

  • Ketamine Hydrochloride Injection, USP
  • Ketamine hydrochloride
  • List of Ketamine Products
  • Special K

Material Safety Data Sheet

  • Ketaset
  • Ketamine Hydrochloride
  • Ketamine Hydrochloride Injection, USP
  • VetaKet® Injection
  • Vetame
  • Ketalar 

Suppliers

  • Suppliers Directory of Ketamine
  • Indian Exporters & Manufacturers of Ketamine
  • Ketamine Hydrochloride Companies List
  • Ketamine Hydrochloride Suppliers
  • Ketamine Manufacturers
  • Manufacturers of Ketamine
  • Exporters of Ketamine

Policies and Rules

  • Ketamine - Schedule III of The Controlled Substances Act
  • Drug laws and rules
  • Illicit Drug Policies
  • Explanatory Memorandum to the Misuse of Drugs

Safety and Risks

  • Facts about Drugs:  Ketamine
  • Indications & Dosage
  • Ketamine Safety Factors
  • Risk Assessment of ketamine in the Framework of the Joint Action on New Synthetic Drugs
  • Dangers and side effects
  • Side Effects & Drug Interactions

Market

  • Other Drugs Market Information
  • The Hong Kong Drug Market
  • State Statutory Approaches to  Illicit Drug Policy
  • Ketamine Usage in the UK 1998-2002

Report

  • Amphetamines and other synthetic drugs in Australia
  • ‘Street ketamine’–associated bladder dysfunction: a report of ten cases
  • Club Drugs: The Latest in the Teen Drug Scene
  • Critical review of Ketamine
  • The Drug Situation Report — 2006
  • National Synthetic drugs Action Plan- Consumption Trends
  • Ten Year Study of Ketamine Psychedelic Therapy (KPT) of Alcohol Dependence

Guidelines

  • Morecambe Bay Shared Care Guideline
  • Frequently Asked Questions About Ketamine
  • Ketamine : Information on Uses, Dosage & Side Effects
  • Useful Links on Ketamine

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