Raw Materials, Extraction Process, Biological Activities, Applications and  Market Reports
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Project Information Profile at a glance

  • Isothiocyanates are largely found locked in the form of glucosinolates and are found largely in cruciferous vegetables such as brocolli and Brussels sprouts, as well as in wasabi and watercress.
  • Isothiocyanates, such as phenethyl isothiocyanate (PEITC) and sulforaphane, have been shown to inhibit carcinogenesis and tumorigensis and as such are useful chemopreventive agents against the development and proliferation of cancers.
  • Allyl isothiocyanate serves the plant as a defense against herbivores; since it is harmful to the plant itself, it is stored in the harmless form of the glucosinolate, separate from the myrosinase enzyme.
  • Cruciferous vegetables are rich in isothiocyanates, which are believed to be the compounds responsible for warding off cancer. Isothiocyanates are eliminated in the body by an enzyme called GST, which is produced by GSTM1 and GSTT1. Therefore, people who have inactive forms of these genes have higher concentrations of isothiocyanates.
  • A method of preparing products including pharmaceutical compositions, food or drink products, supplements or additives, skin or hair products, and agricultural products which contain isothiocyanate oil extracted from glucosinolate-containing plants.
  • No serious adverse effects of isothiocyanates in humans have been reported. Although high dietary intakes of glucosinolates from cruciferous vegetables are not known to have adverse effects during pregnancy or lactation, there is no information on the safety of purified isothiocyanates or supplements containing high doses of glucosinolates and/or isothiocyanates during pregnancy or lactation in humans.

 Content Headlines on CD ROM

  • Phytochemical-Isothiocyanates
  • Isothiocyanates
  • Isocyanates and Isothiocyanates
  • 9-Isothiocyanatoacridine (AcITC)

Raw Materials

  • Broccoli Sprouts
  • Mustard
  • Onions
  • Radish
  • Raphanus sativus
  • Super Broccoli
  • Watercress

Extraction Process

  • Mustard Oil Bomb
  • Method of Extraction of Isothiocyanates into Oil
  • Flavour Components in Rhizome of Wasabi
  • Yield of Isothiocyanates in Wasabi Rhizomes
  • Hydrolysis of Glucosinolates to Isothiocyanates
  • Weed Suppression by Release of Isothiocyanates from Turnip-Rape Mulch
  • GLS Extraction from Yellow Mustard Meal
  • Oil Processing in India
  • Comparison of Four Extraction Methods
  • New Syntheses of Aryl Isothiocyanates
  • Non-Polar Isothiocyanates Extraction From Plants-US Patent
  • Production of Protein Isolates from Hexane-Defatted Ground Yellow Mustard Meal

Biological Activities

  • Allyl Isothiocyanate with Mustard 125 Protein
  • Anticarcinogenic Activities
  • Biosynthesis
  • Conversion of Glucosinolates to Isothiocyanates
  • Isothiocyanate Sulforaphane in Rat
  • Reaction of Allyl Isothiocyanate with Hydroxyl/ Water Using Ultraviolet Spectrometry


  • Effects of Isothiocyanates
  • Generation and Succeeding Reactions of Allenyl
  • ITCS Pre-Harvest Effects
  • Combined Application of Methyl Isothiocyanate and Chloropicrin


  • How Isothiocyanates Help Protect Against Cancer
  • Chemoprevention of Cancer by Dietary Isothiocyanates
  • Dietary Isothiocyanates-Colon Cancer
  • Dietary Organic Isothiocyanates- Human Breast Cancer
  • Human Metabolism and Excretion of Cancer
  • Protect Human Cells against DNA
  • Selected Isothiocyanates Rapidly Induce Growth
    Inhibition of Cancer Cells
  • Induction of Apoptosis
  • Dietary Intake of Isothiocyanates
  • Nutrition and Cancer
  • Methyl Isothiocyanate Volatilization
  • Membrane Transport of Dietary Phenethyl Isothiocyanate by ABCG2

Market Reports

  • Glucosinolate Report-2002
  • Urinary Isothiocyanate Excretion in Shanghai, China
  • Fresh Market and Processing Cabbage
    Germplasm Evaluation Results-2000
  • MTT Annual Report-2004
  • Prevention of Cancer in the Next Millennium
  • Broccoli Compounds Halted Lung Cancer in Animal Tests
  • Determination of Abundance and Activity of Slugs, Snails and Earthworms with Mustard Oil and Shelter Traps
  • Cruciferous Vegetables
  • Compounds from Vegetables Attack Cancer Cells - NZ Research

Project Profiles

  • Nutraceutical Value of Mustard
  • From Genetic Code to Ecological Interactions- Project Proposal
  • Combining Methyl Isothiocyanate, Composts, and Brassica Amendments to Control Southern Blight of Tomato
  • Cancer Prevention Research Projects
  • Dr. Daniel Gregory-Organic Photochemistry
  • New Pharmaceutical Extraction Process
  • Horseradish and Related Nutraceutical Processing Criteria
  • Australia Projects


  • 2,6-Dimethylphenyl Isothiocyanate Suppliers
  • Isothiocyanates Suppliers
  • Isothiocyanates Worldwide Suppliers

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