- In the development
of biodegradable elastomeric polymer called poly(glycerol-sebacate)
(PGS) prepared by polycondensation of glycerol and sebacic acid. To
facilitate nanopatterning of the polymer by molding methodologies, we
chemically modified the PGS through the incorporation of acrylate side
groups to form the linear poly(glycerol-sebacate-acrylate) (PGSA).
- To fabricate
photocurable biodegradable elastomers at room temperature, a three step
process was employed. In the first step, a pre-polymer from glycerol and
sebacic acid was created. In a second step, functional hydroxyl groups
on backbone of the PGS pre-polymer were acrylated and subsequently
purified. In a third step, the PGS-acrylate (PGSA) was polymerized with
UV light in the presence of a photoinitiator. This elastomer is referred
to as photocured PGSA.
- PGSA can be cured
rapidly at ambient temperatures to form polymeric networks with a wide
range of mechanical properties and in vitro
enzymatic degradation and
hydrolysis profiles.
- The porous PGSA
scaffolds can provide a logistical template for 3D growth of cells and
tissue engineering. The porous scaffold prepared from a photocurable
elastomer,poly(glycerolcosebacate) acrylate (PGSA).
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Process &
Product
- Branched and
crosslinked resorbable polymers based on lactic acid, lactide and
caprolactone
- A tough
biodegradable elastomer
- Nicodom IR
Polymers
- Plastic Part
Marking Algorithm
Technology
- Micro- and
nanoscale technologies for tissue engineering and drug discovery
applications
- Biodegradable
Microfluidics: A New Platform for Tissue Engineering
- Biodegradable
microfluidic scaffolds for vascular tissue engineering
- Endothelialized Microvasculature Based on a Biodegradable
Elastomer
Applications
- Development of Photocurable Degradable Elastomers for
Biomedical Applications
- Biomimetic
Nanostructured Medical Adhesives
- A
biodegradable and biocompatible gecko-inspired tissue
adhesive
- Synthesis and
Characterization of Photocurable Elastomers from
Poly(glycerol-co-sebacate)
- A porous
photocurable elastomer for cell encapsulation and
culture
- A Muscle Stent
for Damage Repair
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Properties &
Functions
- Influence of
storage conditions and type of plasticizers on ethylcellulose and
acrylate films formed from aqueous dispersions
- Polymer
properties
- Polymer
Synthesis by In Vitro Enzyme Catalysis
Project &
Report
- Application of
Biorubber to urological implants for drug delivery
- Photo cross linkable
Networks with Tunable Mechanics
- Lessons from the lizard on making a good tissue
adhesive
- Department of Chemical & Biomolecular
Engineering-Research Report
Regulations
- Food and drug
administration-Resinous and polymeric coatings for polyolefin
films
- Resinous and
polymeric coatings for polyolefin films-Food and Drug
Administration
- Materials and
articles in contact with food regulations
- Subject to
effluent limitations and standards for the organic chemicals, plastics
and synthetic fibers point source category
- Threshold of
regulation exemptions
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