- A growth medium or
culture medium is a substance in which microorganisms or cells can
grow.There are different types of media for growing different types
of cells.
- Types of growth
media are: Nutrient media , Minimal media , Selective media ,
Differential media .
- There are two major
types of growth media: those used for cell culture, which use specific
cell types derived from plants or animals, and microbiological culture,
which are used for growing microorganisms, such as bacteria or yeast.
The most common growth media for microorganisms are nutrient broths and
agar plates; specialized media are sometimes required for microorganism
and cell culture growth.
- Cell culture
technology is rapidly evolving. At first these developments mainly
occurred at a laboratory scale, since the culture media requirements for
the propagation of animal cells are very complex and in fact are still
largely unknown for many cell types.
- Complex media are
rich in nutrients, they contain water soluble extracts of plant or
animal tissue (e.g., enzymatically digested animal proteins such as
peptone and tryptone). Usually a sugar, often glucose is added to serve
as the main carbon and energy source. The combination of extracts and
sugar creates a medium which is rich in minerals and organic nutrients,
but since the exact composition is unknown, the medium is called
complex.
- One of the most
critical and important raw materials for biopharma is culture media and
is directly proportionate to the growth of the industry. The culture
media (for both microbial and cell culture) is growing at over 20
percent. The present decade has shown tremendous growth and investment
in the pharmaceutical sector in India as well as globally. The growth
potential observed pertains mainly to regulated markets.
- The quality of the
media depends directly upon the quality
of the raw materials used for
their preparation. Water is the most important raw material used for
the preparation of culture media. The parameters to be checked are
presence of copper ions, conductivity and pH. Ideally there should be
no copper ions present in water because it is inhibitory for
the growth of microorganisms.
- Many processes have
been developed using plant suspension cultures as a result of the ease
in scale-up and application of traditional optimization strategies
developed for microbialand mammalian cell systems. However, secondary
metabolite production is often higher in differentiated tissues; thus
hairy root cultures that have been transformed genetically with
Agrobacterium spp. have also been widely used.
- Globally there are a
handful of companies that deal in culture media. In microbiological
culture media, we have BD, Merck, Oxoid and bioMerieux while in cell
culture media, the players include Invitrogen, Sigma and Cambrex.
- Several Indian
biopharma companies are at the sourcing end for these markets, and these
are the ones that require quality assured, consistent and cost-effective
raw material supplies with various quality systems and certification
program.
- The
worldwide cell culture market is estimated at $1.02 billion in 2005 and
is expected to grow at a compound annual rate of 12.7 percent to cross
$1.86 billion by 2010. With advances in product development, demand for
specialty and custom serum-free media, particularly in biomanufacturing
applications, will drive market growth.
- In
India, companies like Sigma Aldrich, Invitrogen, HyClone, Alfa Laval,
HiMedia Labs, Cambrex, Corning Life Sciences are offering a range of
products and services in cell culture space.
- According to industry sources, it is difficult to estimate
the size of the cell culture sector as companies offer different range
of products and services like media, vessels, cell lines, reactors etc.
The sector is expanding and will see a double-digit growth in the near
future, with the entry of pharmaceutical companies into the
biopharmaceuticals sector.
- Culture media play a
pivotal role in any microbiology
laboratory. They are widely employed
for isolation, identification and sensitivity testing of different
pathogenic microorganisms |
General
- pH in cell
cultures
- Culture Media Index
- Functions of Serum
in the Culture Medium
- Growth
medium
- Plant tissue
culture
- Tissue Culture Media
- Tissue
culture
Material Safety Data
Sheet
- Powdered Plant
Tissue Culture Media
- HyQ-CCM™ 1 Cell
Culture Media
- CCM5 Cell
Culture Media
- Liquid Cell Culture
Media
- Fetal Bovine Serum
(FBS) for Use in Murine Myeloid Long-Term Culture Medium
- System Culture
Media
- Prepared Culture
Media
- Human & Animal
Stem Cell Culture systems
- Horse Serum for Use
in Mouse Myeloid Long-Term Culture Medium
Products
- Culture Media For
Molecular Biology
- Culture Media, Salts
and Vitamin Mixes
- Irvine Scientific
Culture Media
- Bacterial Media and
Cell Culture Related Products
- Cell Culture Media
- Tissue Culture
Media, Reagents and Associated products
- Culture Media
- Chromogenic &
Fluorogenic Culture Media
Technology
- Cell culture
solutions for biomanufacturing
- Cell Culture Media
- OptiCell Concept for
Cell Culture Operations
- Use of plant
hydrolysates in animal cell culture media formulations
-
- Improved culture media could advance stem cell
research
Patent
- Animal cell culture
media comprising peptides derived from rice
- Cell Culture Media
Formulated in Unit Dose
- Culture medium for
the detection of E. coli and process for its use
- Hematopoietic cell
culture nutrient supplement
- Process of microwave
sterilization of culture media for selection of recombinant
microorganisms
- Process for
Recovering Useful Substances from Culture Media
- Ready made
Sterilized Culture Media and Process of Preparation
- Culture Media
Device
- Methods for
Completing a Cell Culture Medium with a Lipophilic Substance
- Solid culture medium
for microorganisms, process for its preparation, and
Preparation
Process
- An Efficient
Approach to Cell Culture Medium Optimization
- DMEM Media
Preparation
- Preparation of
Culture Media
- Tissue Culture Methods
- Building New Culture
Media for Assisted Reproductive Technology
- Genomic and
Proteomic Tools for the Development of Cell Culture Media
- Salt Free Culture
Media
- Sterile Filtration
of Cell Culture Media
- Preparation
and Storage of Culture Media
- Preparation of
Tissue Culture Media
- Waste Water
Reduction from the Culture Medium Preparation Step of an Antibiotic
Production
Machinery
- The BioProfi le FLEX
analyzer
- Autoclavable
Fermentation Systems
- Autoclave
Manufacturers & Suppliers
- Ball Mill
Manufacturers
- Media and Cell
Systems for Epithelial Tissue Culture
- Sieves
Suppleirs
- Bioprocessing system
- Cell Culture Media
Prep System
- Cell surface counter
receptors are essential components of the unconventional export
machinery of galectin-1
|
Market
- Market
for culture media growing at over 20 percent
- Cell Culture Media
Firms Offer Contract Services
- Current Trends and
Innovations in Cell Culture
- Novozymes applies
recombinant technology to cell culture market
- Biopharma industry boosting cell culture sector in
India
- Stem Cell Culture:
Opportunities in an Emerging Market
Company
Profile
- Bio Tina GmbH Life
Science
- Biotecnica
- Caisson Laboratories
- HyClone
- AES Chemunex
- Blulux Laboraotires P Ltd
- Expression Systems
LLC
- Miltenyi
Biotec
- Alpha
Biosciences
- Alpha
Labchem
Plant
Details
- Low Cost Plant
Tissue Culture
- NNE cell culture
plant
- Phyton
Biotech
- Sheffield Pharma
Ingredients
- Titan
Consultants
- Biologics Process
Development
- Bionique Testing Laboratories, Inc.
- Experts
- Breeder Design
Culture Media Consulting International
- PendoTECH
Applications
- Plant Cell Culture
for Production of Paclitaxel and Other Taxanes
- Production and
engineering of terpenoids in plant cell culture
- Influence of culture
media and environmental factors on mycelial growth and pycnidial
production of Sphaeropsis pyriputrescens
- Application of
Serum-Free Culture Medium for Preparation of A-NK Cells
- CHO Host Cell
Proteins from Culture Media
- Culture Medium for
the Production of Staphylococcal Enterotoxin A
- Method for
Evaluating Broth Culture Media: Application to Haemophilus
Guidelines and
Certificates
- Guidelines for
Assuring Quality of Medical Microbiological Culture Media
- Beef Extract Powder
Certificate
- Quality Control of
Culture Media in a Microbiology Laboratory
- Meat Peptones
Certificate
- Guidelines for
Assuring Quality of Solid Media
- Toxicology Test
Guidelines
Reports
- Tips and tricks on
freezing cells
- Biological
Bulletin
- A Study of the Shelf
Life of Critical culture Media
- High Zinc
Concentrations in Culture Media Affect Copper Uptake and Transport in
Differentiated Human Colon Adenocarcinoma Cells
- CELLine Technical
Report I
- CELLine Technical
Report V
- CELLine Technical
Report VI
Projects
- Designing Culture
Media for
Recombinant Protein Production
- Tissue Culture
Laboratory
- In vitro culture of
Heterzostera tasmanica and Zostera muelleri
- Design of Experiment
(DOE) Approach in Cell Culture Medium Optimization
- Neural stem Cell
Culture Model
Suppliers and
Buyers
- Central
Drug House (P) Ltd.,
- Selling
Leads
- Cell Culture Media,
Growth Factors Suppliers
- Suppliers of tissue
culture media
- Dehydrated
culture media Suppliers
- Buyers
List
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