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Project at a Glance Contents on the CD ROM
  • Polyanhydrides are a class of biodegradable polymers characterized by anhydride bonds that connect repeat units of the polymer backbone chain.
  • Their main application is in the medical device and pharmaceutical industry. In vivo, polyanhydrides degrade into non-toxic diacid monomers that can be metabolized and eliminated from the body.
  • Owing to their safe degradation products, polyanhydrides are considered to be biocompatible.
  • Over the past two decades, polyanhydrides have been investigated for short-term controlled delivery of the bioactive agents because they exhibit rapid degradation in vivo and have limited mechanical properties .
  • Polyanhydrides are the hydrophobic polymers with hydrolytically labile anhydride linkages, in which the degradation rate can be manipulated by varying polymer composition.
  • Polyanhydrides are known to undergo surface erosion, a desired property to attain near zero-order drug
    release profile .
  • Recently, due to their biocompatibility and biodegradability, the Food and Drug Administration has approved the use of the polyanhydride derived from sebacic acid and 1,3-bis(p-carboxyphenoxy) propane as the carrier of antitumor agents for the treatment of brain cancer .
  • One drawback of
    polyanhydrides is that most of them have to be stored at frozen state under the anhydrous condition
    because of the hydrolytic instability of the anhydride bond.
  • The main advantage of using polyanhydrides for medical applications is that they gradually degrade into nontoxic, small molecular weight products after their
    intended use in drug delivery, obviating the need for retrieval.
  • The most widely used tech- nique for polyanhydride synthesis is melt polycondensation, which occurs in two steps.
  • In the first step, dicarboxylic acid monomers react with excess acetic an- hydride to form acetyl-terminated anhydride prepolymers with a degree of polymerization.
  • The activated monomers are then polymerized at an elevated temperature (if necessary) under vacuum to yield polyanhydrides
  • Introduction
  • Polyanhydrides
  • Drug delivery systems
  • Synthesis, Characterization and properties study on Novel  Fluorescence Polyanhydrides

MSDS & Products

  • Polysebacic anhydride
  • Zemac E60
  • Ricon 131MA20
  • Polyazelic polyanhydride
  • Hysol ES1301
  • Cytec - product
  • Gliadel - product


  • Polyanhydrides with therapeutically useful degradation products
  • Polyanhydrides
  • Aromatic polyanhydrides
  • Unsaturated polyanhydrides
  • Branched polyanhydrides
  • Fatty acid terminated polyanhydrides
  • Styrene-grafted polyanhydride copolymer
  • Thermosettable epoxide-polyanhydride compositions
  • Polyanhydrides with biologically active degradation products
  • Controlled drug delivery high molecular weight polyanhydrides

Company profiles

  • Company from China
  • Company from New Jersey
  • Company from P.R.China
  • Company from Texas
  • Company from U.S.A
  • Another Company from U.S.A


  • Consultancy from Florida
  • Consultancy from North America
  • Consultancy from U.K
  • Online Consultancy
  • List of Experts
  • Experts list


  • Synthesis and characterization of novel polyanhydrides with tailored erosion mechanisms
  • Polyanhydride synthesis techniques
  • Synthesis and erosion properties of PEG containing polyanhydrides
  • Synthesis and degradation characteristics of salicylic acid derived polyanhydride esters
  • Synthesis and cytotoxicity of salicylate based polyanhydride esters

Raw material & Polyanhydride suppliers

  • Acetic anhydride
  • Dicarboxylic acid
  • Suppliers of Polyanhydrides
  • Suppliers list


  • Xenogenics received rights to Polyanhydride compounds drug delivery patent
  • Biodegradable polymers
  • Polyanhydrides
  • Small angle X-ray scattering to discern microstructure of semicrystalline polyanhydrides for drug delivery
  • A review of photocrosslinked polyanhydrides in situ forming degradable networks
  • Poly(ester-anhydride): poly(amino ester) micro and nanospheres
  • Photocrosslinked polyanhydrides for spinal fusion
  • Erosion and release from biodegradable polyanhydrides
  • Degradable polymer microspheres for controlled drug delivery
  • Crosslinked amino acid containing polyanhydrides for controlled drug release applications
  • Bioerodible polyanhydrides for controlled drug delivery


  • Toxicological studies of Polyanhydride nanoparticles for oral drug delivery
  • Surface and bulk modifications to photocrosslinked polyanhydrides to control degradation behaviour
  • Erosion kinetics of hydrolytically degradable polymers
  • Encapsulation, stabilization and release of BSA-FITC from polyanhydride microspheres
  • Crosslinked polyanhydrides for use in orthopedic applications
  • Controlled release of polypeptides from polyanhydrides
  • Polyanhydride blends as drug delivery matrices to control biofilms, bone and nerve regenerations
  • Biodegradable polymers for microencapsulation of drugs
  • Study on the degradation rate of polyanhydride for potential drug delivery and tissue engineering
  • Analysis of fatty acid anhydrides and polyanhydrides

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