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Project at a Glance

Contents on the CD Rom

  • St John's wort refers to the species Hypericum perforatum, also known as Tipton's Weed or Klamath weed, but, with qualifiers, is used to refer to any species of the genus Hypericum. Therefore, H. perforatum is sometimes called Common St. John's wort to differentiate it.
  • St. John’s Wort has been used in folk medicine since the Middle Ages. It was used by mouth to reduce inflammation, to ease stomach pain, to help sleeplessness, as  a diuretic, to ease nerve pain, for headaches, and to treat anxiety. It was applied to the skin to treat bruises, muscle pain, mild
    burns, smooth white spots on the skin, and for hemorrhoids. Recently, St. John’s Wort has been used to treat mild depression.
  • Pressurized solvent extraction is a new technique that reduces solvent consumption and sample preparation time.The fast PSE is an automated system which processes six samples simultaneously. The parallel processing technology of the fast PSE dramatically increases sample throughput compared to Soxhlet and pressurized solvent extraction systems that employ serial processing. In addition to rapid extraction times, significant reduction in solvent consumption is achieved.
  • The extracts of St. John´s wort Hypericum perforatum L .ssp. angustifolium from the new locality, Sobina, (the surroundings of Vranje, South Serbia, Yugoslavia) obtained by high pressure extraction with CO2, exert antimicrobial action, where the extract obtained under higher pressure exerted stronger action
  • St. Johnswort (Hypericum perforatum L.) isutilized as a bulk raw material by the herbal products industry, where fresh flowers and flowering tips are manufactured into dried extract.
  • The market for Saint John’s Wort varies with world demand and production. Saint John’s Wort cameinto the limelight in 1997 when it was featured onthe television program 20/20. The commercial cropin Europe was less than projected and the resulting effect was that prices soared to the $20.00/lb. (US)level within one week. Saint John’s Wort continuesto be an important herb in the North American andEuropean medicinal markets but prices swings aremuch less than in 1997. Prices in 1999 varied from $5.00-13.00/US/lb. for small lots and were as low as$1.50/lb. US for large lots. It is imperative thatthorough market research be carried out and potentialbuyers be located and communicated with prior toharvesting this crop.
  • In modern medicine, standardized Hypericum extract (obtained from H. perforatum) is commonly used as a treatment for depression and anxiety disorders
  • The active therapeutic ingredients in St. John's wort are hypericin, pseudohypericin and xanthones, although other components may support the action of these compounds. St. John's wort extract preparations are standardized to 0.3 percent hypericin. The typical adult dosage is 300 milligrams taken three times a day, and that means that a person taking St. John's wort gets 2.7 milligrams of hypericin a day.
  • Traditionally, extracts of St. Johns Wort (which contain hypericin) have been used as an antidepressant, possibly by acting as a MAO inhibitor. The psychotropic effects attributed to hypericin in St. Johns Wort extract suggest that the pigment compound can cross the blood brain barrier
  • In accordance with the legend of wound healing during the Crusades, we find agreement in modern times. St. Johns Wort today has been found to be very beneficial in healing wounds and is especially good for dirty, septic wounds. St. Johns Wort has been used in case of putrid leg ulcers, that noting heals. Like the leach that was used not too many years ago for wound cleansing it does not destroy the healthy tissues and healthy cells but it cleans the dirt out of septic wounds.
General Information
  • Common St. John’s Wort
  • St. John’s Wort Factsheet
  • Hypericum spp
  • St John's wort - identification
  • Herb-medicine interactions
  • Herbs at a Glance
  • St John's wort

Properties and Benefits

  • Morphological, chemical and biochemical characterization of St. John’s Wort
  • Physical and Chemical Properties of Commercial Hypericum perforatum Extracts
  • A review of its chemistry, pharmacology and clinical properties
  • Benefits
  • Herbal Relief for Depression
  • Effectiveness

Material Safety Data Sheet

  • St. Johns Wort oil, Infused
  • Tincture Alcohol
  • Trauma Remedy
  • St. John's Wort
  • Hypericum Oil, Infused

Products

  • St. John's Wort Capsules
  • St John's Wort for anxiety
  • Time-Release St. John’s Wort
  • St. John’s Wort oil
  • Remotiv film-coated tablets
  • Depeze
  • St. John's Wort Hypericum perforatum
  • Herbalife

Management

  • St John’s Wort - Statutory Weed Management Plan
  • Management Guide
  • Control and Management
  • Heavy infestation of St John’s wort.
  • Harvest, Storage and Processing
  • Managing St John's wort

Extraction Process

  • Extraction of Hypericin from St. John’s Wort
  • High Pressure Extraction With CO2
  • Raw Material to Finished Product
  • An Antiviral Active Principle of St. Johns Wort
  • Superior efficacy of St John's wort extract
  • Analysis of the hypericin
  • The Determination of Dianthrones in St. John's Wort
  • A Review of the Hypothetical Biogenesis and Regulation of  Hypericin synthesis

Solvent and Machinery

  • Acetonitrile Suppliers
  • Analytical Balance Manufacturers & Suppliers
  • Extraction Machinery Manufacturers
  • Cellulose Filter
  • UV- Vis

Patent

  • Delivery of Hypericum Perforatum in Tablet Form
  • Plantago Major and  Hypericum Perforatum Compound for Use in Treating a Tobacco or Nicotine Habit
  • Methods for making Hypericum fractions and St. John's Wort products
  • Process for the gentle recovery of extract fractions from hypericum
  • Stable extract of Hypericum perforatum L.,process
  • St. John's wort composition

Projects

  • NEPA for Chemical Control Efforts for Noxious Weeds
  • Improving control of St
    John's Wort in a local common
  • Planning for Profit
  • Focus on local alternatives
  • Update on research relating
    to the toxin hypericin produced by St John’s wort
Market
  • Marketing
  • Export Market Opportunities in the USA
  • St. John’s Wort Covered in New York Times
  • St. John’s Wort -Herbs and Dietary Supplements -Ephedra-Part II
Guide
  • Talking to patients about St. John’s wort
  • St. Johns Wort Uses, Dosage & Side Effects
  • St. John’s Wort and the Treatment of Depression
  • St. John’s Wort and Pregnancy
  • St. John’s Wort
  • Guidelines
  • St John's Wort - Info
  • Hypericum wort Guidelines
  • St. John's Wort Extract

Applications

  • Historical St. John's Wort Applications
  • St John's wort - a natural remedy for depression?
  • Remedy or Ruse
  • Medicine
  • St. John's Wort Uses
  • Common Uses
  • Reliable Treatment for Depression.
  • Therapeutic Applications
  • St John's wort protein found to suppress HIV in lab

Growers and Nurseries

  • Dabur
  • Greenwood Nursery
  • Monrovia
  • Mountain Rose Herbs
  • Southern Growers
  • Mountain Valley Growers
  • Woodcreed Farms

Suppliers

  • Changsha Natureway Co., Ltd
  • St. John's Wort Extract Suppliers
  • Greenwoods Herbal Extract Co., Ltd
  • Hypericin
  • St john's wort Selling Leads
  • Selling Leads
  • St. Johns wort P.E Suppliers
  • Xian Chongxin Natural Bio - Products Co., Ltd

Reports

  • Export Market Opportunities in the USA
  • Harvesting Drugs From Medicinal Plants
  • Boosting the Quality and Potency of St. John’s wort
  • St. John's wort - quack medicine or novel antidepressant treatment?
  • Journal Editorial Raises Herbal Concerns
  • St. John’s Wort
  • St John's Wort - Overview
  • Story on St. John's Wort
  • Uses And Dangers Of St. John's Wort
  • St. Johns Wort and all

Risk

  • Adverse Effects of St. John's Wort
  • Side Effects and Cautions
  • St. John’s Wort Poisoning in Livestock
  • Safety and Efficacy
  • St. John's Wort and BP - Unsafe
  • Risk of Drug Interactions
  • St. John's wort
  • St. John’s Wort warning

Consultants

  • Anne Chiotis
  • Eco Terra Landscape Consultants
  • Herbal Consultation
  • Unicho & Greenfield
  • Wilhelmsen Consulting

 

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