Capsidiol
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Project at a Glance Contents on the CD ROM
  • Capsidiol is a terpenoid compound that accumulates in tobacco Nicotiana tabacum and chili pepper Capsicum annuum in response to fungal infection.
  • Capsidiol is categorized under the broad term of phytoalexin, a class of low molecular weight plant secondary metabolites that are produced during infection.
  • Capsidiol is produced in the pepper fruit Capsicum annuum or tobacco Nicotiana tabacum after infection by the oomycete water-mold Phytophthora capsici.
  •  In pepper or tobacco fields, the fungus is soil-borne and initially infects roots, collars and lower leaves. Sporangia are moved within fields by contact with field equipment, clothing, gloves, tools etc. and initial infections spread zoospores through splashing of water from irrigation or rain.
  • Capsidiol is a bicyclic terpene that is biosynthetically derived from the mevalonate pathway via farnesyl pyrophosphate (FPP).
  • Exogenous treatment with H2O2 alone has been shown to induce capsidiol production. Capsidiol production is then increased in response to radical oxygen species production.
  • The sweet pepper phytoalexin capsidiol is metabolized to an appreciable extent by healthy pepper tissue.
  • Capsidiol, a sesquiterpene is produced by peepers in response to infection with a range of fungi and has many of the properties postulated for phytoalexins.
  • In pepper and tobacco, the bicyclic sesquiterpene capsidiol represents the main type of phytoalexin.
  • Capsidiol is synthesized from farnesyl diphosphate via a two-step process catalyzed by 5-epi-aristolochene synthase and 5-epi-aritolochene hydroxylase.
  • In Wild type plants the biosynthesis of capsidiol is accompanied by decreased bioactive abscisic acid.
  • Incorporation of radioactivity from acetate into capsidiol was reduced following elicitor treatment of a trichodiene-producing transformant as compared with wild type.
  • It is a fungitoxic sesquiterpenoid that is produced in tobacco cell-suspension cultures in response to specific elicitors.
  • Capsidiol accumulation for AgNo3 in the callus tissues was higher than the accumulation in the filtrat. But CuSo4 caused more capsidiol accumulation in the filtrat than the tissue.
 Introduction
  • Capsidiol.
  • Capsidiol Production in pepper fruit.
  • Metabolic Engineering of Terepnoid in plants.
  • Capsidiol Biosyntesis flowchart.

Production

  • Elicitation of Red Pepper Suspension Cell for the production o f Capsidiol.
  • Capsidiol production in peppar fruits induced by arachidonic acid.
  • Capsidiol and ethylene production by tobacco cells.
  • Effect of Metalaxyl on Capsidiol production in stems of pepper plants.

Synthesis

  • Synthesis of Capsidiol in Wild Tobacco.
  • Abscisic acid-dependent regulation of capsidiol biosynthesis.
  • Callus suspension cultures of different pepper genotypes.
  • Characterization of novel sesquiterpenoid biosynthesis in tobacco.
  • Stress regulation of gene expression for plastid and cytosolic isoprenoid pathways in pepper fruits.
  • Formation of capsidiol in capsicum annum fruits.
  • Induction of Sesquiterpenoid biosynthesis in tobacco cell.
  • Enzyme Catalyzing Successive Hydroxylations of Sesquiterpenes.
  • Capsidiol accumulation in vitro callus suspension cultures of peppers.

Study

  • Metabolism of  Capsidiol by sweet pepper tissue.
  • Local and Systemic gene expression of Sesquiterpene phytoalexin biosynthetic enzymes.
  • Lipid Changes in tobacco cell .
  • Induction of defense response against colletotrichum capsici in chili fruit.
  • Evidence that 13-hydroxycapsidiol is not an intermediate in capsidiol degradation in peppers.
  • Capsidiol accumulation in cell suspension cultures of capsicum annuum.
  • Capsidiol synthesis in cell suspension cultures of pepper.

Company Profile

  • Company from China.
  • Company from Gujarat.
  • Company from HongKong.

Consultants & Suppliers

  • Capsidiol Experts.
  • Online Suppliers.

Patents

  • Anticancer Agents.
  • Composition and regime for treating the adverse signs of cutaneous skin aging.
  • Cytochrome P450S and Uses.
  • Plants Experssing chimeric isoprenoid synthases.
  • Therapeutic uses of pungent botanicals and their related compounds.
  • Synergistic anti-hypertensive phyto-nutraceutical composition.

Report & Uses

  • Biotransformation of the sesquiterpene valencence by cytochrome.
  • Cross-protection of pepper plants stressed by copper against a vascular pathogen.
  • Differential induction of sesquiterpene metabolism in tobacco cell.
  • Functional Characterization of premnaspirodiene oxygenase.
  • The Mechanism of the antibacterial action of Glycinol, a phytoalexin synthesized by soyabeans.
  • Isolation of an elicitor-stimulated synthase gene from chili pepper.
  • New constituents of sweet capsicum and evaluation of  their biological activity.
  • Capsidiol, an Antifungal compound from Peppers.

 

 

 

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