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  • Chlorhexidine is a chemical antiseptic.
  • It kills both gram-positive and gram-negative microbes, although it is less effective with some gram-negative microbes.
  • It is also bacteriostatic.
  • Chlorhexidine in high concentrations must be kept away from eyes and the inner ear, although it is used in minute concentrations in some contact lens solutions.
  • The mechanism of action is believed to be membrane disruption, and not ATPase inactivation as previously thought.
  • Chlorhexidine is deactivated by anionic compounds, including the anionic surfactants .
  • It has been shown to have an immediate bactericidal action and a prolonged bacteriostatic action due to adsorption onto the pellicle coated enamel surface.
  • It is sometimes marketed under the brand names Peridex, Periochip or Periogard Oral Rinse.
  • In the UK it is mainly marketed under the brand name Corsodyl ; in Germany as Chlorhexamed; in Australia as Savacol; in India as Clohex or Dejavu-MW.
  • It is often used as an active ingredient in mouthwash designed to kill dental plaque and other oral bacteria Chlorhexidine can thus be used to improve bad breath.
  • The antiseptic chlorhexidine is widely used both in everyday life and in the hospital environment.
  •  It is usually well tolerated, and there are scarce reports of allergic reactions in our environment.
  • It is commonly used as detergents & toothpastes.
  • It is also a component of the household antiseptic Savlon.
  • It is used for general skin cleansing, a surgical scrub and a pre-operative skin preparation.
  • Due to other chemicals listed as inactive ingredients, the cleanser solution is not suitable for use as mouthwash.
  • It is often used as a rubbing agent prior to the use of hypodermic or intravenous needles in place of iodine.
  • Chlorhexidine is contraindicated for use near the meninges, in the genital area, and near the eyes and ears.
  • Chlorhexidine


  • Controlled Release of a Bactericidal Ceragenin-Polymer Conjugate
  • Cytotoxicity of chlorhexidine digluconate to murine macrophages and its effect on hydrogen peroxide and nitric oxide induction
  • Synthesis of deuterium-labelled chlorhexidine
  • Evaluation of a Teat Dip of Chlorhexidine Digluconate (.5%) with Glycerin (6%)
  • Analysis of the Effects of Chlorhexidine on Oral Biofilm Vitality and Structure Based on Viability Profiling and an Indicator of Membrane Integrity
  • Susceptibility of Chlamydia trachomatis to Chlorhexidine Gluconate Gel


  • A randomized trial that compared povidone iodine and chlorhexidine as antiseptics for vaginal hysterectomy
  • Disinfection of Eyelid Specula With Chlorhexidine Gluconate (Hibiclens) After Examinations for Retinopathy of Prematurity
  • Effect of Smear Layer and Chlorhexidine Treatment on the Adhesion of Enterococcus faecalis to Bovine Dentin
  • Impact of Chlorhexidine–Silver Sulfadiazine-Impregnated Central Venous Catheters on In Vitro Quantitation of Catheter-Associated Bacteria

Consultant & Company Profile

  • Chlorhexidine Consultant
  • Chlorhexidine Expert
  • Consultant From Finland
  • Consultant From Thailand
  • Consultant From Turkey
  • Consultant From USA
  • Company From Spain


  • Chlorhexidine Gluconate Cloth
  • Chlorhexidine Rinse
  • Formulating a chlorhexidine based shampoo
  • Antiseptic/Antimicrobial Skin Cleanser
  • Chlorhexidine
  • Chlorhexidine Solution


  • Composition Comprising Mupirocin & Chlorhexidine
  • Film - Forming Composition Containing Chlorhexidine
  • Chlorhexidine Gluconate - Containing Stabilized aqueous Pharmaceutical preparations
  • Modified Chlorhexidine Adduct
  • Chlorhexidine Formulation, New chlorhexidine salts, Solutions Containing these & their Use
  • Water - soluble, chlorhexidine Containing Composite & use Thereof


  • Chlorhexidine Dihydrochloride
  • Chlorhexidine Digluconate
  • Chlorhexidine
  • Safety data for chlorhexidine
  • Chlorhexidine Scrub
  • Chlorhexidine Solution


  • A Comparison of the Effect of Chlorhexidine, Tap Water and Normal Saline on Healing Wounds
  • Effectiveness of Root Canal Debris Removal Using Passive Ultrasound Irrigation with Chlorhexidine Digluconate or Sodium Hypochlorite Individually or in Combination as Irrigants
  • Infections in implantology
  • The Effect of Chlorhexidine Gluconate as an Endodontic Irrigant on the Apical Seal Long-term Results
  • Pin Site Care
  • Chlorhexidine Gluconate


  • Acute urticaria due to chlorhexidine
  • Guidelines for Rodent Survival Surgery
  • Chlorhexidine Vaginal and Neonatal Wipes in Home Births in Pakistan
  • Infection Prevention
  • Results of gastro scope bacterial decontamination by enzymatic detergent compared to chlorhexidine
  •  Hygiene Tips

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