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Information @ a Glance

Contents on the CD Rom

  • Diazepam is a "classical" benzodiazepine derivative drug.
  • Other classical benzodiazepines include clonazepam, lorazepam, oxazepam, alprazolam, nitrazepam, flurazepam, bromazepam and clorazepate.
  • Diazepam, first marketed as Valium by Hoffmann-La Roche.
  • Diazepam possesses anxiolytic, anticonvulsant, sedative, skeletal muscle relaxant and amnestic properties.
  • Diazepam occurs as solid white or yellow crystals.
  • Diazepam can absorb into plastic, and therefore diazepam solution is not stored in plastic bottles or syringes etc.
  • Diazepam works by acting on receptors in the brain called GABA receptors. This causes the release of a neurotransmitter called GABA in the brain.
  • Electron-capture gas chromatography or reversed-phase “high-performance” liquid chromatography is used for concurrent analysis for diazepam and nordiazepam in serum.
  • The psychomotor recovery of patients sedated with either midazolam or Diazepam has been compared using the digit symbol substitution test and the Trieger test.
  • Open-heart operations with cardiopulmonary bypass, anaesthetized by using primarily the combination of diazepam with pentazocine.
  • Diazepam is mainly used to treat anxiety, insomnia, and symptoms of acute alcohol or opiate withdrawal.
  • Diazepam is rarely used for the long-term treatment of epilepsy.
    Diazepam is used as a short term sedative and anxiolytic for cats and dogs.
  • Diazepam is also used as a muscle relaxant for horses.
    Diazepam increases the central depressive effects of alcohol, other hypnotics/sedatives (e.g. barbiturates), narcotics, and other muscle relaxants.
  • Diazepam-binding inhibitor(DBI) mediates the postprandial rise in plasma cholecystokinin-releasing peptide(CCK) levels.
  • High-dose diazepam reduces prime-induced activation of alcohol-related words(ALC) concepts in problem drinkers.
  • The heat effect associated with the binding of diazepam to human serum albumin has been measured using flow microcalorimetry technique.
  • The effect of diazepam on respiration has been investigated by the modification of the rebreathing CO2-challenge technique.
  • The drug diazepam is measured by gas-liquid chromatography technique, with use of an electron capture detector.
  • HPLC method is developed for identification and simultaneous determination of diazepam and preservatives (benzyl alcohol and benzoic acid / sodium benzoate).
  • An estimated 38,000 addicts of substances such as heroin using benzodiazepines in Scotland, increasing the risk of death.
  • Across the UK have struggled for years to come off benzodiazepines after being legally prescribed them
General Information
  • Diazepam - Drug information
  • About Diazepam
  • Valium
  • Diazepam

Company Profiles & Consultant

  • Company from India
  • Company from New Jersey
  • Company from Virginia
  • Consultant from Illinois
  • Consultant from Italy
  • Consultant from Minnesota

Synthesis & Process

  • Analysis for Diazepam and Nordiazepam by Electron-Capture Gas Chromatography and by Liquid Chromatography
  • Evaluation of Antidotes for Poisoning by Organophosphorus Pesticides - Diazepam
  • Molecularly imprinted polymer for solid-phase extraction of diazepam and its metabolites from hair samples
  • A randomized comparison of midazolam and diazepam injectable emulsion in cataract surgery
  • Supercritical fluid extraction of diazepam from whole blood using fillers
  • Simultaneous determination of diazepam and preservatives in HPMC hydrogel by HPLC
  • Diazepam (Valium) Synthesis


  • Diazepam-binding inhibitor mediates feedback regulation of pancreatic secretion and postprandial release of cholecystokinin
  • Diazepam dose-dependently increases or decreases implicit priming of alcohol asscociation in problem drinkers
  • Liquid-Chromatographic Assay of Diazepam and Its Major Metabolites in Serum, and Application to Pharmacokinetic Study of High Doses of Diazepam in Schizophrenics
  • Bicuculline, pentobarbital and diazepam modulate spontaneous GABAA channels in rat hippocampal neurons
  • Comparison of the influence of diazepam and new benzodiazepine derivative on the behaviour of rabbits under spontaneous conditions
  • The use of Chirascan to study the competitive binding of diazepam and ibuprofen to human serum albumin (HSA)


  • The pH Dependence of the Thermodynamics of the Interaction of Diazepam with Human Serum Albumin
  • The effect of Diazepam on the respiratory response to carbondioxide
  • Micromethod for Determination of Diazepam by Electron-Capture Gas-Liquid Chromatography
  • A Simple flow injection spectrophotometric procedure for the determination of diazepam in pharmaceutical formulation
  • Diazepam-Pentazocine anaesthesia for cardiovascular surgery
Material Safety Data Sheet
  • Diazepam
  • Diazepam Elixir
  • Diazepam Injection
  • Pamlin Injection
  • Benzphetamine Hydrochloride Tablets 50 mg


  • Apaurin
  • Apo-Diazepam
  • Aspen Diazepam Injection 10 mg/2 mL
  • Diazepam Tablets
  • DiaJect Auto-injector


  • Buccal, Polar and non-polar spray containing diazepam
  • Delivery of diazepam through an inhalation route
  • Diazepam enzyme conjugates
  • Pre-filled injection a barrel wherein a liquid diazepam formulation is accommodated
  • Preparation of diazepam


  • Effects of vitamin C on ketamine-diazepam anesthesia in dogs
  • Effects of Diazepam on Human Pain Tolerance and Pain Sensitivity
  • Influence of ethanol on the myorelaxant effect of diazepam in rat
  • Sedative effect of oral diazepam and chloral hydrate in the dental treatment  of children
  • Brain targeted transcranial route of drug delivery of diazepam


  • Case report: A fugue-like state associated with diazepam use
  • Intravenous Injection of Diazepam to Cubital Vein Can be Complicated by Accidental Intra-Arterial Penetration and Gangrene
  • Diazepam-Ketamine anaesthesia for the surgical management of electric burns in bonnet macaque monkeys - Report of two cases
  • Diazepam in severe tetanus treatment - case report
  • Use of Diazepam for transportations of Himalayan black bear
  • Valium nation investigation by health correspondent judith duffy


  • Rectal Diazepam - Instructions for Home Use
  • South Gloucestershire Drug Action Team Guidelines on good practice in prescribing Benzodiazepines to Drug Users in General Practice
  • Protocol for the administration of  rectal diazepam for named patients by healthcare staff in learning disabilities units
  • Benzodiazepine and Non-Benzodiazepine Guidelines for   General Practice
  • Pediatric dosing guidelines for nerve agents


  • Suppliers of Diazepam
  • Selling leads of Diazepam
  • Exporters of Diazepam


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