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  • Eugenol (C10H12O2), is an allyl chain-substituted guaiacol.
  • Eugenol is a member of the phenylpropanoids class of chemical compounds.
  • It is a clear to pale yellow oily liquid extracted from certain essential oils especially from clove oil, nutmeg, cinnamon, and bay leaf.
  • It is slightly soluble in water and soluble in organic solvents. It has a pleasant, spicy, clove-like aroma.
  • Eugenol is sometimes called clove oil because it is the active element in cloves.
  • Besides cloves, it can also be extracted from cinnamon and other aromatic spices.
  • Its specific gravity is slightly more than 1.06 at room temperature, making it heavier than water.
  • Its boiling point is about 252° C.It has about a 2 year shelf life before its potency begins to seriously degrade.
  • It is recommended that it be stored in a cool, dry, and dark place.
  • Essential oils are volatile, ethereal liquids of oily consistency. They are extracted from plants, usually by steam distilaltion or extraction.
  • Eugenol is the main ingredient of the essential oil that can be isolated from the spice clove.
  • Eugenol contains a carbon-carbon double bond and an aromatic hydroxyl group called a phenol. These functional groups provide the basis for simple chemical tests used to characterize the clove oil.
  • Eugenol is used in perfumeries, flavorings, essential oils and in medicine as a local antiseptic and anesthetic.
  • It is a key ingredient in Indonesian kretek (clove) cigarettes.
  • Eugenol derivatives or methoxyphenol derivatives in wider classification are used in perfumery and flavoring.
  • They are used in formulating insect attractants and UV absorbers, analgesics, biocides and antiseptics. They are also used in manufacturing stabilizers and antioxidants for plastics and rubbers.
  • Eugenol is a phenol derivative that is used in combination with zinc oxide as a surgical dressing,pulp capping agent, cavity liner, temporary cement, and in mouthwashes and endodontic therapy.
  • Eugenol is found as a major ingredient in a variety of dental materials such as impression materials, filling materials, dental cements, endodontic sealers, periodontal dressing materials and dry socket dressings.
  • Eugenol was the compound responsible for antifungal activity of the essential oil of O. gratissimum.
  • The capacity of a zinc oxide-and eugenol-based root canal sealer in penetrating into lateral canals depends on two factors: the physical properties of the material and the correct manipulation of the sealer, respecting the powder-liquid ratio and observing the ideal clinical consistency for obturation, which is more important and, also, more controllable by the dentist.
  • Many benzene derivatives possess aromatic, spicy and specific odors. These aromatic compounds include mono- and polysubstituted
    benzene derivatives, such as benzaldehyde, anethole and anisaldehyde, eugenol and vanillin, safrole and heliotropin.
  • Eugenol is widely used in dentistry. It is generally used without incident however in a sensitised individual it can cause a range of tissue effects, from low-grade local reactions to the rare, but serious, anaphylactic reaction.
  • Eugenol is not a bio-friendly material and patients should be discouraged from using it in its pure form, either to alleviate toothache or dentine hypersensitivity.
  • Eugenol containing materials need to be used in the appropriate amounts and manufacturer's instructions should be followed. For patients who are allergic to eugenol, eugenol-free alternatives are available.
General Information
  • About Eugenol
  • Information about Eugenol
  • Introduction about Eugenol
  • Description about eugenol
  • Clove Description


  • Extraction of Eugenol with Liquid Carbon Dioxide
  • C-Eugenol:Synthesis, Polymerization, and Use
  • Isolation and Characterization of Eugenol
  • Isolation of a Natural Product by Steam Distillation
  • Supercritical CO2 Extraction of Essential Oil from Clove Bud:Effect of Operation Conditions on the Selective Isolation of Eugenol and Eugenyl Acetate
  • Steam Distillation
  • Experimental results for the extraction of essential oil from Lippia sidoides cham using pressurized carbondioxide
  • Isolating cloveoil from cloves using steam distillation
  • Steam Distillation of a Volatile Oil from Cloves

Companyprofiles & Suppliers

  • Company from India
  • Company from Indonesia
  • Company from NewDelhi
  • Suppliers of Eugenol
  • Manufacturers of Eugenol
  • Company from Missouri


  • Consultant from Califonia
  • Consultant from Canada
  • Consultant from Germany
  • Consultant from Macedonia
  • Consultant from England


  • MSDS for Eugenol
  • Safety data for acetyl eugenol
  • Eugenol Liquid
  • Safety data for eugenol
  • Eugenol
  • Clove Oil
  • Chemical data sheet for Eugenol
  • Root Canal Sealer Liquid Eugenol

Application & product

  • Grubbs’s Cross Metathesis of Eugenol with cis-2-Butene-1,4-diol To Make a Natural Product
  • The Efficacy of Clove Oil As An Anesthetic for the Zebrafish
  • Floral Scent Production in Clarkia breweri
  • Adverse reactions associated with the use of eugenol in dentistry
  • Microbial transformation of propenylbenzenes for natural flavour production
  • Application of Eugenol for Coating Soybean Seeds as Fungal Control
  • Methyl Eugenol
  • Dental Cement Systems
  • Vanillin


  • Eugenol enhancement of transdermal drug delivery
  • Phenethyl propionate and eugenol, a potent attractant for the japanese beetle
  • Silicone functionalized eugenol esters
  • Silyl derivatives of Eugenol
  • Method of preparing Vanillin from Eugenol
  • Use of Eugenol in chewing gum as an antioxidant
  • Derivatives of Eugenol as medicaments

Toxicity & Hazards

  • Eugenol oil overdose
  • Eugenol - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information
  • A comparative tissue toxicity evaluation of four endodontic materials
  • Eugenol toxicological study
  • Physical Properties ofSome zinc Oxide-Eugenol Cements
  • Eugenol Lignin: its Chemical Properties and Significance
  • Dielectric Properties of Zinc Oxide-Eugenol Type Cements
  • Antioxidant Activity of Eugenol and Related Monomeric and Dimeric Compounds
  • Synthesis and Properties of the Phthalocyanines Containing Eugenol


  • Antifungal Activity of Essential Oil Isolated from Ocimum gratissimum L.(eugenolchemotype) against Phytopathogenic Fungi
  • Carcinogenesis of Eugenol
  • Effect of Eugenol-Based Endodontic Cement on the Adhesion of Intraradicular Posts
  • Effects of Six Endodontic Cements on the Cells of the Murine Immune System In Vitro
  • Effect of Eugenol on Growth and Listeriolysin O Production by Listeria monocytogenes
  • Influence of the spatulation of two zinc oxide-eugenol-based sealers on the obturation of lateral canals
  • Highly Efficient Biotransformation of Eugenol to Ferulic Acid and Further Conversion to Vanillin in Recombinant Strains of Escherichia coli


  • Production of aroma chemicals
  • Control of Fruit Flies in Horticultural Crops with Special Emphasis on Watermelon fruit fly
  • Evaluation of Splat-mat with spinosad and methyl eugenol or cue-lure for suppression/eradication of oriental and melon fruit flies
  • Public and private partnerships in area-wide fruit fly pest management for the benefit of farmers: The Hawaii experience
  • Pilot project for methyl, eugenol/naled ahbient air monitoring
  • Clove oil for potato sprout and silver scurf suppression in storage
  • The Carciogenic potency project


  • Methyl Eugenol and Cue-Lure Traps for Suppression of Male Oriental Fruit Flies and Melon Flies (Diptera: Tephritidae) in Hawaii: Effects of Lure Mixtures and Weathering
  • Prevention of Isoproterenol-induced cardiac hypertrophy by eugenol, an antioxidant
  • Using Eugenol for Seed Coating Technology as Storage Fungi Controller in Soybean Seeds


  • Report of the Food Quality Protection Act (FQPA) Tolerance Reassessment Progress and Risk Management Decision (TRED) for Methyl Eugenol
  • Ada standad commitee on dental products
  • Methyl Eugenol; Tolerance Reassessment Decision for Low Risk Pesticide; Notice of Availability
  • Dental zinc oxide-eugenol cements and zinc oxide non-eugenol cements
  • Status of Clove Oil and Eugenol for Anesthesia of Fish



  • Ayurveda Awareness
  • Essential Oils and Fragrances from Natural Sources
  • Healing Process of Dog Teeth after Post Space Preparation and Exposition of the Filling Material to the Oral Environment
  • Production, Yield and Derivatives of Volatile Oils from Eastern Redcedar
  • Determination of Eugenol in Mainstream Tobacco Smoke
  • Methyl Eugenol/Naled monitoring at fruit fly trapping locations

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