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Information @ a Glance

Contents on the CD Rom

  • Metronidazole is an antibiotic used to treat different kinds of infections.
  • Metronidazole is a nitroimidazole anti-infective medication used mainly in the treatment of infections caused by susceptible organisms, particularly anaerobic bacteria and protozoa.
  • Metronidazole is a prodrug. It is converted in anaerobic organisms by the redox enzyme pyruvate-ferredoxin oxidoreductase.
  • The nitro group of metronidazole is chemically reduced by ferredoxin  and the products are responsible for disrupting the DNA helical structure, thus inhibiting nucleic acid synthesis.
  • Metronidazole is selectively taken up by anaerobic bacteria and sensitive protozoal organisms because of the ability of these organisms to reduce metronidazole to its active form intracellularly.
  • The deoxyribonucleic acid (DNA)-degrading potential of metronidazole was evaluated in vitro by three techniques determination of melting curve,
    measurementof viscosity, and centrifugation in neutral or alkaline sucrose gradients.
  • Two methods are presented for simultaneous determination of diloxanide furoate and metronidazole.
  •  The first method depends on first derivative of  the ratio-spectra by measurements of the amplitudes at 242.5 and 285.5 nm for diloxanide furoate and 225.5 and 300 nm for metrinidazole.
  • It is marketed by Pfizer under the trade name Flagyl in the US.
  • while Sanofi-Aventis markets metronidazole globally under the same tradename, Flagyl, and also by various generic manufacturers, who sell it at a lower price.
  • Metronidazole has also been used in women to prevent preterm birth associated with bacterial vaginosis, amongst other risk factors including the presence of cervicovaginal fetal fibronectin.
  • A randomized controlled trial demonstrated that metronidazole was ineffective in preventing preterm delivery in high-risk pregnant women and, conversely, the incidence of preterm delivery was actually higher in women treated with metronidazole.
Introduction
  • Metronidazole
  • Metronidazole Flagyl
  • Metronidazole
Process
  • An Appraisal of the Healing Profiles of oral & External (Gel) Metronidazole on Partial Thickness Burn Wounds
  • Effect of core and surface cross-linking on the entrapment of metronidazole in pectin beads
  • Helicobacter pylori acquistion of metronidazole resistance by natural transformation in vitro
  • Mechanisms of in vitro development of resistance to metronidazole in Trichomonas vaginalis
  • Influence of solvent and crystallization method on the crystal habit of metronidazole
  • Spectrophotometric Determination of Metronidazole in Pharmaceutical Pure and Dosage Forms using p-Benzoquinone
Application
  • Prevalence of primary Helicobacter pylori resistance to metronidazole and clarithromycin in Singapore
  • Putative Metronidazole Neurotoxicosis in a Cat
  • Intravenous Metronidazole for Treatment of Infections Involving Anaerobic Bacteria
  • Amperometric Metronidazole Sensor Based on the Supermolecular Recognition by Metalloporphyrin Incorporated In Carbon Paste Electrode
  • Systemic use of metronidazole in the treatment of chronic periodontitis: a pilot study using clinical, microbiological, and enzymatic evaluation
Msds
  • Metronidazole Topical Gel
  • Safety data for metronidazole
  • Metronidazole Msds
  • Metronidazole 

Product

  • Elyzol 25% Dental Gel
  • Metronidazole Gel
  • Metrogel
  • Metronidazole Topical gel
  • Metronidazole cream
Market & Report
  • Bulk Pharmaceutical
  • Demand and Price Dynamics within the Pharmaceutical Benefits Scheme
  • Metronidazole Induced Pancreatitis
  • Dosing regimens in the newborn 

  • Motherisk Update

  • Report of the First Three Cases from Finland and Optimization of In Vitro Susceptibility Testing under Various Oxygen Concentrations
Patent
  • Aqueous topical gel of High Stability Based on Metronidsazole & Method of Preparation
  • Gel Composition Containing Metronidazole
  • Heterovaccine Against the Trichomonas Syndrome, & Process for its Preparation
  • Intra vaginal Treatment of vaginal infections with Buffered Metronidazole composition
  • Novel Antibacterial & antiprotozoal Derivatives, a Process for the Preparation thereof, & related pharmaceutical composition
  • Pharmaceutical Dental formulation for topical application of metronidazole Benzoate, Chlorhexidine Gluconate & local anesthetic
Consultants
  • Consultant From USA
  • Consultant From US
  • Consultant From UK
  • Consultant From USA
  • Consultant From Washington
  • Metronidazole Expert
Suppliers
  • Metronidazole Suppliers
  • Suppliers of Metronidazole
  • Metronidazole Exporters
  • Manufacturers of Metronidazole
Technology
  • Absence of Strand Breaks in Deoxyribonucleic Acid Treated with Metronidazole
  • Determination of Diloxanide Furoate and Metronidazole in Binary Mixture Using First Derivative of the Ratio-Spectra and High-Performance Liquid Chromatography-UV Methods

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