Phytoanticipins 
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Project at a Glance Contents on the CD ROM
  • Preformed antimicrobial compounds are called phytoanticipins
  • Phytoanticipins are unique as they are preformed, rather than being synthesized from remote precursors after pathogen infection (phytoalexins)
  • Phytoanticipins has 2 classes constitutive: saponins (glycosylated antimicrobials) inactive precursors processed after tissue damage or pathogen attack (cyanogenic glycosides and glucosinolates)
  • Fruits contain secondary metabolites with antifungal properties, called phytoanticipins..
  • Phytoalexins and phytoanticipins
    serve both structural and metabolic functions in disease resistance
  • Phytoalexins and phytoanticipins can be as low molecular weight antimicrobial compounds that are synthesized by plants. The major function of PAL is to catalyze phytoalexins and phytoanticipins production and thereby reduce disease severity
  • Phytoanticipins are high energy and carbon consuming and exhibit fitness cost under natural conditions, but recognized as the first line of chemical defense that potential pathogens have to overcome.
  • Phytoanticipins seem adequate for therapeutic use.
  • Phytoanticipins are secondary metabolites produced by fungi and plants
  • Phytoanticipins are preformed
    antifungal secondary metabolites present in the healthy plants. For example, glucosinolates are stored in vacuoles
  • The ultimate objective of investigations studying the relevance of phytoanticipins and phytoalexins in the plant defence response is to develop biotechnological applications in crop protection. Some of the above described phytoalexins provide a potentially interesting weapon to be used in agricultural techniques.
General Information
  • Plant Antimicrobial Agents and Their Effects on Plant and Human Pathogens
  • Elicitors And Phytotoxins From The Blackleg Fungus : Structure, Bioactivity And Biosynthesis
  • Functional diversifications of cyanogenic glucosides
  • Natural products and plant disease resistance

Safety

  • Feasibility Study For Insuring Dedicated Energy Crops
  • Infection Process - Plant Defenses
  • What are the prospects for genetically engineered, disease resistant plants?
  • Safety Evaluation

Study

  • Chemical Study Of the Blackleg Fungus : Metabolites, Phytotoxins And Phytoalexins
  • Plant Defence Compounds Against Botrytis Infection
  • Saponins versus plant fungal pathogens
  • Structural Complexity, Differential Response to Infection, and Tissue Specificity of Indolic and Phenyl propanoid Secondary Metabolism in Arabidopsis Roots
  • Sulphur Deficiency Causes a Reduction in Antimicrobial Potential and Leads to Increased Disease Susceptibility of Oilseed Rape
  • The role of secondary metabolites in Arabidopsis and Brassica in the interaction with fungi

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Synthesis

  • Phytoalexins From Crucifers : Structures, Synthesis And Biosynthesis
  • Phytoalexins: Defence or just a response to stress?
  • Metabolic changes in Arabidopsis thaliana plants overexpressing chalcone synthase
  • Perception and modification of plant flavonoid signals by rhizosphere microorganisms
  • Plant basal resistance: genetics, biochemistry and impacts on plant-biotic interactions
  • Transgenic Tobacco and Arabidopsis Plants Expressing the Two Multifunctional Sorghum Cytochrome P450 Enzymes

Reports

  • Avenacin A-1 Content of Some Local Oat Genotypes and the In Vitro Effect of Avenacins on Several Soil-Borne Fungal Pathogens of Cereals
  • Laccase: new functions for an old enzyme
  • Pathogenicity genes of phytopathogenic fungi
  • Perception and modification of plant flavonoid signals by rhizosphere microorganisms
  • In silico comparison of transcript abundances during Arabidopsis
    thaliana and Glycine max resistance to Fusarium virguliforme
  • Role of secondary metabolites in defense mechanisms of plants
  • Two vacuole-mediated defense strategies in plants

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