- Resveratrol is a
phytoalexin produced naturally by several plants when under attack by
pathogens such as bacteria or fungi.
- Resveratrol has also
been produced by chemical synthesis, and is sold as a nutritional
supplement derived primarily from Japanese knotweed.
- Resveratrol is found in
grapes, wine, grape juice, and berries of Vaccinum species including
blueberries, bilberries, and cranberries.
- Resveratrol’s full
chemical name is 3,4',5-trihydroxystilbene and its chemical formula is
C14H12O3.
- It has cis and trans
isomers. t-resveratrol is most common natural component. The cis isomer,
is less prevalent and little is known about its activity and health
benefits.
- Resveratrol belongs to
a class of polyphenolic compounds called stilbenes. Some types of plants
produce resveratrol and other types of stilbenes in response to stress,
injury, fungal infection, and ultraviolet (UV) radiation.
- Resveratrol is a
phytoalexin whose synthesis occurs in grapes, and in consequence, it can
be found in grape products such as wine and musts and
by-products.
- Resveratrol is a
phenolic compound that has been linked to the beneficial effects of red
wine, which have been proposed to be mimetic of caloric restriction in
mammals.
- Resveratrol contained
in plasma was purified by solid-phase extraction using a C18
cartridge.
- In plants, resveratrol
is produced as a branch from the phenylpropanoid pathway. It is derived
from p-coumaric acid,
which is an intermediate in lignin
production.
- The formation of
resveratrol was followed by HPLC analysis of 5-ml samples during the
growth of the culture.
- trans-Resveratrol
(trans-3,5,4˘-trihydroxystilbene), a phenolic compound present in
grapes, wines, and peanuts, has been reported to have health benefits
including anticarcinogenic effects and protection against cardiovascular
diseases.
-
The HPLC–tandem mass spectrometry method enabled us to
identify resveratrol sulfates in human LDL and to characterize the
complete profile of resveratrol metabolism in human LDL and
urine.
-
The effect of resveratrol on Ca -activated K currents in
an endothelial cell line (HUV-EC-C) originally derived from human
umbilical vein was investigated with the aid of the 1 patch-clamp
technique.
-
The role of resveratrol
and rapamycin as an
anti-carcinogenic drug can be determined using AFM technique
-
Two modern laser-based techniques were synchronously
applied to study the dynamics of the trans-resveratrol activity in
Botrytis cinerea-infected grapes.
- Resveratrol has been
found to inhibit the proliferation of a variety of human cancer cell
lines, including those from breast, prostate, stomach, colon,
pancreatic, and thyroid cancers when added to cells cultured outside the
body.
- Trans-resveratrol is
commercially available and procedures for the purification of the
commercial material (by recrystallization from ethanol/water) have been
developed.
- Resveratrol was added
to the food starting in early adulthood and caused a dose-dependent
increase of median and maximum lifespan.
- In addition,
resveratrol delays the age-dependent decay of locomotor activity and
cognitive performances and reduces the expression of neurofibrillary
degeneration in the brain.
- Many studies have
demonstrated that this molecule exhibits a wide range of biological and
pharmacological activities both in vitro and in vivo.
- Many of the biological
activities of resveratrol, like the inhibition of cyclooxygenase,
induction of CD95 signaling-dependent apoptosis, effects on the cell
division cycle and modulation of NF-?B activation, indicate a possible
effect on immune response and many in vitro experiments have proven that
resveratrol has immuno-modulatory activity.
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General
Information
Resveratrol- Nature’s Longevity
Nutrient and Anti-Cancer Weapon
Resverotrol
Grape Expectations: The
Resveratrol Story
Resveratrol
Information
About
Resveratrol
Production
- Production of Resveratrol in Recombinant
Microorganisms
R esveratrol in plant raw-materials
and food products
Preliminary Results on Contents of
Resveratrol in Wine of Organic and Conventional Vineyards
Elicitor Induced
Resveratrol Production in Cell culture of different grape
genotype
Production and secretion of resveratrol in hairy
root cultures of peanut
Production of
Trans-Resveratrol by grapevine cell suspensions
Synthesis &
Process
Chocolate and cocoa: New sources of
trans-resveratrol and trans-piceid
Determination of trans-Resveratrol in
Plasma by HPLC
Interaction of trans-resveratrol with
endogenous formaldehyde as one basis of its diverse beneficial
biological effects
Molecular Mechanisms of the
Chemopreventive Effects of Resveratrol and Its Analogs in Colorectal
Cancer: Key Role of Polyamines
Cultivar, Juice
Extraction, Ultra Violet Irradiation and Storage Influence the Stilbene
content of muscadine grape
Resveratrol, a Polyphenolic
Phytostilbene, Inhibits Endothelial Monocyte Chemotactic Protein-1
Synthesis and Secretion
Resveratrol: Isomeric Molar Absorptivities and
Stability
Application
Trans-Resveratrol andTrans- -Viniferin with Medicinal and
Anti-Phytopathogenic ε Applications
Resveratrol Improves Mitochondrial
Function and Protects against Metabolic Disease by Activating SIRT1 and
PGC-1a
Resveratrol Oxidation in Botrytis cinerea
Conidia
Radical Scavenging
Activity of Extracts of Argentine Peanut Skins in relation to its
trans-resveratrol content
Resveratrol Promotes Clearance of
Alzheimer’s Disease Amyloid Peptides
Resveratrol in red
wine, is thought to contribute to improved cardiovascular effects
associated with moderate consumption of red wine
Red wine's resveratrol
may help battle obesity
Technology
HPLC–Tandem Mass Spectrometric Method
to Characterize Resveratrol Metabolism in Humans
Resveratrol: Cutting-Edge Technology Available
Today
Evidence for the stimulatory effect of
resveratrol on Ca -activated K current in vascular endothelial cells
Trans-Resveratrol and Grape Disease
Resistance. A Dynamical Study by High-Resolution Laser-Based
Techniques
Application of
Adsorption Resin Technology and FCPC Chromotagraphy for the recovery of
Polyphenols and stilbenoids from grape pomace
Project &
Consultant
- Evaluation of
Resveratrol and Curcumin as Therapeutics against high-risk
leukemia
- Investigation whether
resveratrol, a substrate found only in red wine can provide similar
health benefits within other forms of alcohol, without significant
side-effects.
- Extraction Purification
Project of Resveratrol from Polygonum Cuspidatum
- Investigations of
mechanisms of action of resveratrol (3,4ż,5-trihydroxystilben; component
of red wine) on the cardiovascular system
- Mechanisms of cell cycle regulation by selected
plant-derived compounds.
- Consultant from United
States
- Consultant from
China
- US Consultant from
Louisiana
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Patent
- Compositions Based on
Resveratrol
- Cosmetic Compositions
Containing Resveratrol
- Method for the
production of resveratrol in cell cultures
- Use of a Plant extract
or plant juice
- Method for the
production of resveratrol in a recombinant bacterial host cell
Product &
Material Safety Data Sheet
- Resveratrol
supplement, 10 mg 60 Capsules
Club Natural
- Micronized Resveratrol
- Isotonix Resveratrol
- Resveratrol
- Resveradox™
-
Resveratrol Extra
- Trans -
Resveratrol
- Resveratrol Safety Data Sheet
- Resveratrol MSDS
Function
-
Short communication. Exploring new
functional markets potential: factors affecting willingness to purchase
functional wines
-
Effect of Resveratrol on Some
Activities of Isolated and in Whole Blood Human Neutrophils
- Low dose of resveratrol enhanced immune response
of mice
-
Effects of resveratrol and ethanol on
production of pro-inflammatory factors from endotoxin activated murine
macrophages
-
Vascular Dysfunction in Aging:
Potential Effects of Resveratrol, an Anti-Inflammatory
Phytoestrogen
Protective effect of
Reaveratrol on Ethanol-Induced Lipid peroxidation in rats
Resveratrol Reduces Oxidative Stress
Induced by Platinum Compounds in Blood Platelets
In Vitro Effects of Resveratrol on the
Viability and Infectivity of the Microsporidian Encephalitozoon
cuniculi
Properties
- Adsorption and
Desorption Properties of Trans-Resveratrol on Cellulose Cotton
- Resveratrol as
Anti-aging Antioxidant
-
Estrogenic and Antiestrogenic
Properties of Resveratrol in Mammary Tumor Models
-
Resveratrol as an antioxidant and
pro-oxidant agent: mechanisms and clinical implications
- Substrate-specific Activation of Sirtuins by
Resveratrol
- Antioxidant and
Toxicological Properties of the Phytoalexin Resveratrol
- Synthesis and Anti-inflammatory Activity of
Resveratrol Analogs
Report &
Market
- Resveratrol -
Renaissance
Health Publishing Report
Levels of Resveratrol in 'Concord' Grapes
Resveratrol prolongs allograft
survival after liver transplantation in rats
First Red Wine Antioxidant Supplement,
Resvinatrol Complete™, Now Available in U.S.
Resveratrol Prolongs Lifespan and
Retards the Onset of Age-Related Markers in a Short-Lived
Vertebrate
Resveratrol in Parts of Vine and Wine
Originating from Bohemian and Moravian Vineyard Regions
The Australian
Resveratrol enhanced Wines
Drug Market
Development
Toxicity
Review of
Toxicological Literature- trans-Resveratrol
Antitumor and immunomodulatory
activity of resveratrol on experimentally implanted tumor of H22 in
Balb/c mice
Resveratrol at H igh D oses Acts as an
Apoptotic Inducer in Endothelial C ells
Resveratrol-Associated Renal Toxicity
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