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  • Tetrahydrofuran, also known as THF, is a heterocyclic organic compound with the formula (CH2)4O.
  • Tetrahydrofuran is a colorless low-viscosity liquid with a smell similar to diethyl ether.
  • THF is one of the most polar ethers.
  • THF is the fully hydrogenated analog of the aromatic compound furan.
  • THF is an aprotic solvent with a dielectric constant of 7.6.
  • THF is a moderately polar, aprotic solvent that dissolves a wide range of non polar and polar compounds.
  • THF can be polymerized by strong acids to give a linear polymer called poly (tetramethylene ether) glycol PTMEG, also known as PTMO, polytetramethylene oxide.
  • THF can be synthesized by catalytic hydrogenation of furan.
    The major industrial process for making THF is the acid-catalyzed dehydration of 1,4-butanediol.
  • Du Pont developed a process for producing THF by oxidizing n-butane to crude maleic anhydride, followed by catalytic hydrogenation of maleic anhydride to THF.
  • THF or diethyl ether are often used as solvents for Grignard reagents because of the oxygen atom's ability to coordinate to the magnesium ion component of the Grignard reagent.
  • THF is often used in polymer science.
  • THF can be used to dissolve rubber prior to determining its molecular mass using gel permeation chromatography.
  • THF dissolves PVC, and is the main ingredient in PVC adhesives.
  • THF can be used to liquefy old PVC cement.
  • Exposure to THF is most likely to occur in occupational settings through inhalation or by dermal contact.
  • THF has been detected in ambient air, groundwater, drinking water, landfill sludge, and in some common household products.


  • Tetrahydrofuran
  • Tetrahydrofuran fact sheet


  • Synthesis of 2,5-Disubstituted Tetrahydrofurans by Stereo specific Elimination-Cyclization of 1-Iodomethyl-1,5-bis-epoxides
  • Diastereo selective synthesis of tetrahydrofuran-containing fragments by the permanganate oxidation of 1,5,9-trienes
  • Graphitization-induced micro structural changes in tetrahydrofuran-derived pyrolytic carbon spheres
  • Polycondensation of Tetrahydrofuran with Phthalic Anhydride Induced By a Proton Exchanged Montmorillonite Clay
  • Simulation of the Tetrahydrofuran Dehydration Process by Extractive Distillation in Aspen Plus
  • Synthesis of Tetrahydrofuran and Tetrahydropyran Derivatives Catalyzed by Tungstophosphoric Acid in Ionic Liquid
  • Tailored synthesis of branched polymers with poly(tetrahydrofuran) having an azetidinium salt end group


  • Tetrahydrofuran
  • Interaction of Tetrahydrofuran with Athabasca Bitumen
  • Executive Summary
  • Tetrahydrofuran Storage & Handling


  • Suppliers of Tetrahydrofuran
  • Tetrahydrofuran Suppliers
  • Manufacturers of Tetrahydrofuran
  • Tetrahydrofuran Distributors
  • Tetrahydrofuran Manufacturers


  • Tetrahydrofuran Msds
  • Tetrahydrofuran
  • Tetrahydrofuran Msds
  • Safety Data For Tetrahydrofuran
  • Tetrahydrofuran
  • Tetrahydrofuran Msds


  • Method of preparing tetrahydrofuran
  • Process for the preparation of tetrahydrofuran
  • Purification of tetrahydrofuran
  • Process for refining tetrahydrofuran
  • Tetrahydrofuran-2-ylmethylamines and fungicidal and plant growth regulating use
  • Tetrahydrofuran derivatives and their use as NK-1 antagonists


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Company Profile

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Application & Technology

  • Tetrahydrofuran Ring-opening with Acyloxyphosphonium Bromide Catalyzed by Zinc Bromide: An Effective Method for the Preparation of 4-Bromobutyl Esters
  • Ultra fine fibers of polystyrene dissolved in tetrahydrofuran prepared using the electro spinning method
  • Living polymerization of a-methyl styrene in tetrahydrofuran followed by dynamic light scattering near its polymerization temperature
  • Cryo-electrochemistry in tetrahydrofuran: The electrochemical reduction of a phenyl thioether

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