Chlorpyrifos                              General, Process, Functions, Company Profiles, Patent, Material Safety Data Sheet, Report                                             Primary Information Services                                                     Home. Ordering Information. Contact

• Chlorpyrifos is a toxic crystalline organophosphate insecticide that inhibits acetylcholinesterase and is used to control insect pests.
• Trade names include Dursban (home and garden uses) and Lorsban (agricultural uses).
• Chlorpyrifos belongs to a class of insecticides known as organophosphates.
• The crops with the most intense chlorpyrifos use are cotton, corn, almonds, and fruit trees including oranges and apples.
• Chlorpyrifos can kill insects by direct contact or ingestion. Chlorpyrifos kills insects by disrupting their normal nervous system functions.
• Chlorpyrifos disrupts the nervous system by phosphorylating the active site of the acetylcholinesterase enzyme, rendering it inactive.
• People can be exposed to chlorpyrifos by direct dermal contact, contact with treated surfaces, ingestion of chlorpyrifos contaminated dust, and by
  breathing air inside or outside treated buildings or near fields where it was applied.
• Chlorpyrifos is moderately to very highly toxic to birds, honeybees, fish, and aquatic organisms.
• Chlorpyrifos has been one of the pesticides most used worldwide since 1965.
• Chlorpyrifos is an irreversible inhibitor of cholinesterase (ChE), and inhibition of ChE is believed to be the most sensitive effect in all animal species evaluated and in humans.
• Chlorpyrifos (CPF) and diazinon (DZN) are inhibitors of acetylcholinesterase due to the effects of their active oxygen analogs.
• Chlorpyrifos is an organophosphate insecticide, acaricide and miticide used to control foliage and soil-borne insect pests on a variety of food and feed crops.
• Diazinon and chlorpyrifos are commonly found in consumer and commercial products marketed for urban uses. These uses are generally related to lawn/garden care, indoor pest control, and pet care products.
• Chlorpyrifos and other organophosphates such as diazinon have immediate, direct inhibitory actions on DNA synthesis and hence on neural
  cell replication, with preferential targeting of gliotypic cells. The active metabolite, chlorpyrifos oxon, is less effective than chlorpyrifos, indicating that the antimitotic effects are separable from inhibition of cholinesterase.
• Approximately 10 million pounds are applied annually in agricultural settings. The largest agricultural market for chlorpyrifos in terms of total pounds ai is corn (~5.5 million).
• In agricultural applications, chlorpyrifos is registered to control a broad range of insect pests across many crops. In domestic and commercial settings it is registered for the control of pests such as termites, fleas and cockroaches.
• Chlorpyrifos is a broad-spectrum organophosphate insecticide. It is registered for use in Australia for crop protection and pest control.

• Chlorpyrifos
• Molecular Structure - Chlorpyrifos
• Chlorpyrifos Fact sheet

Process

• Biodegradation of Chlorpyrifos by Enterobacter Strain B-14 and Its Use in Bioremediation of Contaminated Soils
• Degradation of bifenthrin, chlorpyrifos and imidacloprid in soil and bedding materials at termiticidal application rates
• Detection of Chlorpyrifos in Bananas
• The Organophosphate Pesticide
  Chlorpyrifos Affects Form
  Deprivation Myopia
• Health-Based Investigation Level for Chlorpyrifos
• Neurologic Function among Termiticide Applicators Exposed to Chlorpyrifos
• A Simple HPLC Method for the
  Determination of Chlorpyrifos in Black Oil Sunflower Seeds
• Respiratory strategy is a major determinant of water and chlorpyrifos uptake in aquatic insects
• Whole System Perspective: Steelhead, Onchorhynchus mykiss, Glutathione S-Transferase as a Biomarker of Chlorpyrifos Exposure

Functions

• Effect of Chlorpyrifos on the Nutritive Value in a Freshwater Field Crab, Spiralothelphusa hydrodroma
• Lower Birth Weight as A Critical Effect of Chlorpyrifos: A Comparison of Human and Animal Data
• Effect of Metalaxyl and Chlorpyrifos-Methyl Against Early Blight and Whitefly In Tomato and Eggplant
• Impact of Chlorpyrifos on the Neurosecretory Cells in a Freshwater Field Crab, Spiralothelphusa hydrodroma
• The In Vivo quantitation of Diazinon, Chlorpyrifos, and their major metabolites in Rat blood for the refinement of a physiologically based pharmacokinetic/ Pharmacodynamic modelsandrea
• Developmental Neurotoxicity of Chlorpyrifos Modeled in Vitro: Comparative Effects of Metabolites and Other Cholinesterase Inhibitors on DNA Synthesis in PC12 and C6 Cells
• Effects of Soil pH on the Biodegradation of Chlorpyrifos and Isolation of a Chlorpyrifos-Degrading Bacterium
• Efficacy of monomehypo 5G and Chlorpyrifos 40EC against insect pests and their effect on natural enemies in rice eco-system

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