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Contents on the CD Rom

  • Metformin Hydrochloride is an anti-diabetic preparation.
  • Metformin hydrochloride is a white, crystalline powder which is odourless or almost odourless and hygroscopic.
  • It is freely soluble in water, slightly soluble in ethanol (96%), and practically insoluble in chloroform and ether.
  • The chemical name for metformin hydrochloride is 1,1-dimethylbiguanide hydrochloride.
    Metformin is an oral biguanide hypoglycaemic agent.
  • Metformin is a hepato-selective insulin sensitizer.
  • Metformin is excreted unchanged in the urine and does not undergo hepatic metabolism.
  • A simple and rapid HPLC assay method for the estimation of metformin in human plasma was developed and validated.
  • Extended release (ER) formulation of metformin hydrochloride (HCl) investigates the possibility for development of a direct compression ER matrix tablet using hypromellose.
  • The synthesis, characterization and pharmacodynamic evaluation of the copper [Cu2+] and nickel [Ni2+] complexes of metformin have been studied.
  • Metformin may be used as initial treatment or in sulfonylurea failures either alone or in combination with a sulfonylurea and other oral agents.
  • Metformin hydrochloride is an oral biguanidine, which reduces the elevated blood glucose concentration in patients with diabetes but does not
    increase insulin secretion.
  • Metformin hydrochloride is a high-dose drug widely used as an oral anti-hyperglycemic agent.
  • Small size and improved release technology has evolved the therapy of metformin. Thus, metformin still is used as a therapeutic agent of first choice
    for monotherapy of the typical overweight patient.
  • A simple, rapid and precise method is developed for the quantitative simultaneous determination of metformin hydrochloride and rosiglitazone
    maleate in a combined pharmaceutical-dosage form.
  • A high performance reverse phase liquid chromatographic procedure is developed for the Simultaneous estimation of Metformin Hydrochloride and Pioglitazone hydrochloride in combined tablet dosage form.

General Information

  • Metformin - Data Sheet
  • Metformin Hydrochloride IP/BP/ Ph.Eur/USP
  • Metformin hydrochloride - Drug Information
  • Metformin Hydrochloride
  • Metformin
  • Metformin Hydrochloride - Product Information
  • Rosiglitazone maleate with Metformin hydrochloride

Plant

  • Plant from China
  • Plant from India
  • Plant from Mumbai

Process

  • Metformin Hydrochlodride analysis
  • Estimation and pharmacokinetics of metformin in human volunteers
  • Investigation of a Directly Compressible Metformin HCl 500mg Extended Release Formulation Based on Hypromellose
  • Copper and Nickel complexes of Metformin: Synthesis, Characterization and Pharmacodynamic Evaluation

Technology

  • Metformin: Old Wine in New Bottle - Evolving Technology and Therapy in Diabetes
  • Simultaneous estimation of Metformin Hydrochloride and Pioglitazone hydrochloride by RPHPLC method
  • Simple and rapid method determination for metformin in human plasma using high performance liquid chromatography tandem mass spectrometry: Application to pharmacokinetic studies
  • Simultaneous High-performance Liquid Chromatographic Determination of Metformin
    Hydrochloride and Rosiglitazone Maleate in Pharmaceutical-dosage Form

Patent

  • Metformin hydrochloride tablets
  • Directly compressible extended-release matrix formulation for metformin hydrochloride
  • Extended release metformin hydrochloride formulations
  • Direct compression metformin hydrochloride tablets
  • Liquid formulation of metformin

 

Company Profiles & Consultant

  • Company from Michigan
  • Company from Mumbai
  • Indian Company from Tamilnadu
  • Company from Norway
  • Consultant from USA
Material Safety Data Sheet & Product
  • Metformin HCL
  • Metformin Hydrochloride
  • AVANDAMET®
  • GLUCOPHAGE®
  • GLUMETZA™
  • Metformin Hydrochloride Tablets
  • Walaphage GP

Function & Uses

  • Metformin improves liver antioxidant potential in rats fed a high-fructose diet
  • Pharmaceutical equivalence of metformin tablets with various binders
  • Tolerability and pharmacokinetics of metformin and the dipeptidyl peptidase-4 inhibitor sitagliptin when co-administered in patients with type 2 diabetes

Quality & Report

  • Ranbaxy granted marketing approval for metformin HCl extended release 500 mg tablets
  • Quality, safety and efficacy of Pioglitazone / Metformin hydrochloride
  • Psoriasiform drug eruption associated with metformin hydrochloride: A case report
  • Guidelines for Metformin Hydrochloride and Intravascular Contrast Media
  • Public Assessment Report Decentralised Procedure Metformin Hydrochloride 500 mg/5 ml Oral Solution

Suppliers

  • Metformin Hydrochloride Suppliers
  • Selling leads of Metformin Hydrochloride
  • Exporters of  Metformin Hydrochloride
  • Metformin Hydrochloride suppliers worldwide
  • Metformin Hydrochloride manufacturer / Suppliers

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