- Keratin is one of structural protein composing our stratum
corneum, hair and nail. Specially it comprises 80% of human’s hair.
In terms of its amino acid composition, it has cystine which rarely
seen in any other kinds of protein. In association with disulfide
bond, it has very unique molecular structure that peptide is well
cross-linked. Because of this structure, much functional end group
such as amino groups and carboxyl groups exist within a single
molecule. Consequently, high adsorption can be arose from Keratin.
It gives hair strength and body
- The main sources of Keratin ingredients are sheep wool and
bovine hoof (nail) or horn.8 Goat (cashmere) wool and bird (chicken)
feathers may also be used. Human hair was once a major source of
Keratin, but its use is now limited because of the European ban on
human-sourced materials for cosmetics. These differing sources could
potentially produce or result in keratin with unique properties,
which may result in varying compositions and impurities within a
single ingredient (e.g., Keratin from human hair may have some
impurities that are different from Keratin obtained from bird
feathers)
- Keratin proteins extracted from hair are classified into 3 broad
groups: alpha, beta, and gamma.12 α-Keratin (found in hair fiber
cortex) is low in sulfur content and has an average molecular weight
of 60-80 kDa. β-Keratin is protective and forms the majority of the
hair cuticle; this type of keratin is difficult to extract.
γ-Keratin is globular, high in sulfur content, and has a molecular
weight of ~15 kDa
- The keratin-derived ingredients function mainly as skin and hair
conditioning agents
in personal care products. There are the following 8 keratin-derived
ingredients:
Hydrolyzed Keratin
Hydrolyzed Hair Keratin
Hydrolyzed Oxidized Keratin
Hydrolyzed Sulfonated Keratin
Keratin
Oxidized Keratin
Soluble Keratin
Sulfonated Keratin
- Keratins are difficult to solubilize compared to other proteins.
After mechanical means of processing, such as grinding of materials
like animal horn, one of the first known processes for extracting
keratins involved harsh (caustic) conditions using lime. Eventually,
a number of oxidative and reductive methods were developed for
extracting keratin.
- Hydrolyzed Keratin may be prepared from sheep wool. The wool is
first washed to remove soil and debris and then boiled to remove
residual oils. Next, the wool is enzyme-hydrolyzed under mild
conditions for 4-6 hours. When the target molecular weight is
reached, the pH is adjusted to neutralize the enzyme. The resultant
solution is a mixture of Hydrolyzed Keratin fractions with a
molecular weight of ~ 1000 Da. The solution may be diluted to
produce a 30% active material
- Keratin which is obtained from biomass like human hair, nails,
animals, horns, claws, hooves, feather, wool, hoof and outer layer
of skin and plant such as maize, wheat and rice
has vast applications in pharmaceutical industry.
- These animal keratin and phytokeratin can be used very safely on
human being. This is one of the major step for the reducing the
waste of biomass including plants and animals.
|
Basics
Keratin in Human Hair
-
About Human
Hair
-
Materials in Hair
-
Melanosomes
-
Amino Acids in Human
Hair
-
Human
hair protein, cuticle fragment and hydroxyapatite
Companies in the
field
- Company
& Products
- Product of USA
- Keratin
Powder manufacturer
- Keratin
Powder
- Hydrolysed keratin
- Distributor
- Manufacturer - Protein Hydrolysates
- Company - Silky Hair Serum
- Company - Argan Instant Keratin
- AC Keratin Hydrolysate
Keratin
Extraction
-
Extraction,
Confirmation and Applications of Protein from Human Hairs - Lab
Scale
-
A Pilot-Scale Study on the
Extraction & Optimization of Keratin from Human Hair
-
Keratin extraction from human hair by
sulfitolysis
-
Purification
procedure for keratin
-
Human hair keratin hydrogel : fabrication,
characterization and application
-
Purification
procedure for keratin-associated proteins and keratin from human
hair
-
Keratin
extraction from Human Hair
-
Extraction of Keratin from Human Hair with
Production of Biofertilizer
-
Comparison of
Methods for Extraction of Keratin
-
Development of
Keratin based Organo-apatites as Bone-mimetic Biomaterials
-
Keratin:Zein particles
Patents
- Biomaterials
from Human Hair
- Human
derived Keratin Hair Filler composition
Project
Information
- Bio fertilizer
from Human Hair
- Kit for the
quantification of keratin in mammalian hair
-
Supplier
- Hair Products
-
Human Hair
supplier
Applications & Market Scenario
- Pharmaceutical &
Cosmetical Application of Keratin
- Bio Fertilizer
from Human Hair
- Safety Assessment
- Plant
derived Keratin
- Keratin Colour
- Distributor - India
- Keratin and Sericin: State
of the Art and Future Outlook
- Consultant -
Market Reports
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