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Project at a Glance

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  • Monoclonal antibodies(mAbs) are just like antibodies except they are artificially produced from the clones of a single cell.
  • Monoclonal antibodies are made by multiple, identical copies (i.e. clones) of a cell called a hybridoma.
  • Monoclonal antibodies are produced by fusing single antibody-forming cells to tumor cells grown in culture. The resulting cell is called a hybridoma.
  • Monoclonal antibodies are created with cell fusion technology and cell culture technology .
  • Once a monoclonal antibody is made, it can be used as a specific probe to track down and purify the specific protein that induced its formation.
  • Monoclonal antibodies can be used to classify strains of a single pathogen, e.g. Neisseria gonorrhoeae can be typed using monoclonal antibodies.
  • Monoclonal antibodies are widely used as diagnostic and research reagents. Their introduction into human therapy has been much slower.
  • Monoclonal antibodies (MABs or MOABs) work on cancer cells in the same way natural antibodies work, by identifying and binding to the target cells.
  • The market for therapeutic monoclonal antibodies (mAbs) is one of the most dynamic sectors within the pharmaceutical industry.
  • The current global clinical antibody pipeline, which comprises 132 products in development and is dominated by humanized (42%) and fully human (28%)mAbs, is poised to deliver as many as 16 new products between 2004 and 2008.
  • As a result of growth in existing markets for mAb therapeutics,and the opening of new ones, the global market is projected to increase to US $16.7 billion in 2008.
  • The mAbs market is expected to almost triple in value over the next six years from $10.3 billion in 2004 to $30.3 billion. Oncology products will continue to dominate the market. However, sales of arthritis, immune and inflammatory disorders (AIID) products are forecast to grow strongly and account for 40.1% of the market by 2010.
  • Chimeric mAbs were the undisputed leaders,with 43% growth and US $3.8 billion in sales, followed by humanized
    mAbs with more than US $1.4 billion in sales and growth of 29%.
  • The development focus of the industry is moving away from murine and chimeric antibodies, to humanized and, in particular, fully human technologies. A wave of fully human products are expected to launch from 2007 onwards, accounting for 12 of the 20 launches between 2007 and 2010.
  • Roche and Genentech dominate the mAbs market, with a combined market share of 44.9% in 2004, although this is forecast to slip to 35.7% in 2010.
  • Next generation antibodies are forecast to drive the market towards the $30 billion mark by 2011 due to a high level of innovation in early-stage discovery and several potential nichebusters set to launch in the next 5 years.
  • Applications of Monoclonal Antibodies include: Identification of Cell Surface Markers , Detection Assays , Purification Techniques , Gene Identification , Disease Therapy , Use in Applied Chemistry
General Introduction
  • Monoclonal antibodies - Discovery
  • Monoclonal Antibodies
  • Monoclonal Antibodies - FAQ
  • Monoclonal Antibodies - Q&A
  • Monoclonal Antibody Form and Function
  • Monoclonal Antibodies - Procedure


  • Advances in Monoclonal Antibody Technology
  • Antibody Technology Developments
  • Monoclonal Antibody Technology Developed by China
  • Monoclonal antibody technology - Definition and Scoper
  • Cambridge Antibody Technology
  • Monoclonal Antibody Technology
  • New Antibody Production Technology
  • ECVAM Workshop
  • Tech Transfer
  • Monoclonal Antibody Technology - The Basics

Technology Offers

  • EMBL Technology Transfer
  • Mabtech AB Technology Offer
  • Cambridge Antibody Technology Group plc  Offer
  • Innovative technology for production of monoclonal antibodies
  • MorphoSys Technology Offering
  • Stem Cell Isolation - Technology Offer
  • Rapid separation of free target cells by the use of magnetic beads
  • Technology Offers from Israel
  • Method for Separating Viable (Eurcaryotic) Cells from Cell Suspensions
  • Vaccinex, Inc. Technology Offer

Production and Guidelines

  • Guidelines for the Production of Polyclonal and Monoclonal Antibodies
  • Regulatable systemic production of monoclonal antibodies
  • Guidelines on Monoclonal Antibody Production
  • In Vivo Monoclonal Antibody Production Guidelines
  • Production of murine monoclonal anti-B
  • Production and Characterization of Monoclonal Antibodies against Vegetative Cells of Bacillus cereus
  • Production of Monoclonal Antibody Specific for Human Hemoglobin
  • Large scale production of monoclonal antibodies
  • Monoclonal Antibody Production


  • Price List
  • Strategies for Monoclonal Antibody Therapy 2004
  • Antibodies 2005
  • Monoclonal Antibody Successes in the Clinic
  • The Monoclonal Antibody Story Continues
  • Economic impact of  applications of monoclonal antibodies to medicine and biology
  • The Future of Monoclonal Antibody Therapeutics
  • Monoclonal antibodies market
  • Manufacturing Unit for Monoclonal Antibodies
  • Monoclonal Antibodies in Fish and Shellfish Health Management in India
  • Research Project
  • Competitive Enzyme-Linked Immunosorbent Assay
  • Role of Antibody in Protection Against Listeria monocytogenes
  • Environmental Management Science Program
  • Modified lysozyme as a potential alternative to
    antibiotics in animal production
  • Prevalence of Fluorescent Monoclonal Antibody
  • Monoclonal Antibody Production Services
  • Monoclonal Antibody Development Services
Company Profiles
  • Elusys Therapeutics, Inc
  • Companies Load Up On Magic Bullets
  • Epitomics Inc.,
  • Leinco Technologies
  • Medarex
  • NeoClone
  • Company and Institute Resources Providing New Technologies
  • Monoclonal Antibody Suppliers
  • Ablynx
  • Biocytex
  • Biodesign International
  • Cambridge Antibody Technology
  • Biolex, Inc.
  • Cell Sciences
  • Genmab
  • Glycart Biotechnology
  • CuraGen Corp.
  • ImClone Systems
  • Oxford Biotechnology Ltd.
  • Progenics Pharmaceuticals Ltd.
  • Symphogen
  • TNB Laboratories Inc.
  • TolerRx


  • High-Affinity Monoclonal Antibodies for Aflatoxins and Their Application to Solid-Phase Immunoassays
  • Alternatives to Monoclonal Antibody Production
  • Clinical Applications of Monoclonal Antibodies
  • Clinical Laboratory Applications of Monoclonal Antibodies
  • Monoclonal Antibodies and Therapies
  • Origins of Monoclonal antibody therapy
  • Monoclonal antibody-based immunodot test for epizootic ulcerative syndrome pathogen, Aphanomyces invadans
  • Therapeutic Applications
  • Monoclonal Antibodies Uses
  • Application of the Monoclonal Antibodies
  • Application of Monoclonal Antibodies to Vibrio cholerae 0139 Synonym Bengal
  • Preparation and Primary Application of Monoclonal Antibodies
  • Production and Application of Monoclonal
    Antibodies to Human Selenoprotein P
  • Monoclonal Antibodies Used as Reagents in Drug Manufacturing
  • Spectrum of Applications of Monoclonal Antibody Therapy
  • Monoclonal Antibodies for the Detection of Integrins
  • Immunogenicity of Monoclonal Antibody Products
  • Monoclonal Antibodies for Research and Clinical Use
  • Monoclonal Antibody Therapy


  • Report of the Committee on Methods of Producing Monoclonal Antibodies
  • Monoclonal Antibody-Based Therapies
  • The Cochrane Renal Group
  • Elmar Schnee on the Pharmaceuticals business sector
  • Millipore - Annual Report
  • Short Report
  • ImmunoafRnity Purification of S-Antigen Using Monoclonal Antibodies to Different Antigenic Sites


  • Professor Akabani's
  • Experts
  • BioAnalab
  • Consultant
  • D-Gen Consultants
  • Dr. Jessop
  • Panel of Distinguished Scientific Consultants
  • Mr. Peter Probst
  • Consultants in Nuclear Medicine
  • Vicor's Officers and Consultants


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