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. Trifluoroacetic acid . Ordering Information. Contact

Project at a Glance Contents on the CD ROM
  • TFE or trifluoroethyl alcohol, this colourless, water-miscible liquid has a smell reminiscent of ethanol.
  • Due to the electronegativity of the trifluoromethyl group, this alcohol exhibits a stronger acidic character compared to ethanol. Thus, TFE forms stable complexes also with heterocycles (e.g. THF or pyridine) through hydrogen bonding.
  • Trifluoroethanol is produced industrially by hydrogenation or the hydride reduction of derivatives of trifluoroacetic acid, such as the esters or acid chloride.
  • Uses :- A non-aqueous co-solvent that serves as tool to study protein
    folding. It is also used in various pharmaceutical, chemical and
    engineering applications.
  • Trifluoroethanol is used as a solvent in organic chemistry. Oxidations of sulfur compounds using hydrogen peroxide are effectively conducted in TFE. Protein denaturant.
  • In biology TFE is used as a co-solvent in protein folding studies with NMR spectroscopy: this solvent can effectively solubilize both peptides and proteins.
  • Depending upon its concentration, TFE can strongly affect the three-dimensional structure of proteins.
    Industrially trifluoroethanol is employed as a solvent for nylon as well as in applications of the pharmaceutical field.
  • Oxidation of trifluoroethanol yields trifluoroacetaldehyde or trifluoroacetic acid. It also serves as a source of the trifluoromethyl group for various chemical reactions
  • TFEA As A Solvent :-
    TFEA is miscible with many oxygen Containing Compounds such As water, alcohols, ethers and ketones.It also dissolves certain Aromatic Compounds such As Benzene and Toluene
  • Energy Fields :-
    TFEA exhibits Both Extremely Tough Stability as well desirable thermodynamic Properties.TFEA has only found limited use in waste thermal energy recovery systems
  • Anesthetics :- The Synthesis Of medical Anesthetics is the most important known Application For TFEA Certain Ether Derivatives Of TFEA have Been Used As Medical Anesthetics.
General Information
  • Introduction Of Trifluoroethanol
  • Production Process And Applications


  • 2,2,2-Trifluoroethanol
  • 2,2,2-Trifluoroethanol-d3, 99+ atom%
  • 2,2,2-Trifluoroethanol
  • 2,2,2-Trifluoroethanol
  • TFE; 2,2,2-Trifluoroethyl alcohol
  • 2,2,2-Trifluoroethanol


  • Process For the Preparation Of Trifluoroethanol
  • Process For Making Trifluoroethanol
  • Method For Removing Trifluoroethanol From Liquids
  • Trifluoroethanol As a Male Contraceptive
  • Piperidyl Phenyl Trifluoroethanols

Company Profiles 

  • Company From China
  • Company From Hebei Province
  • Company From Jiangsu Province


  • Technology From Japan


  • Suppliers Of Trifluoroethanol
  • Manufacturers Of Trifluoroethanol
  • Trifluoroethanol Suppliers List
  • Distributers Of Trifluoroethanol
  • Wholesalers Of Trifluoroethanol


  • Consultancy From China
  • Consultancy From India
  • Consultancy From UK


  • 2,2,2-Trifluoroethanol Toxicity in Hamsters
  • 2,2,2-Trifluoroethanol Toxicity in Aged Rats

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  • Dediazoniation Reactions as Potential Routes to Fluoroaromatics.
  • A direct and rapid route to a,a-difluoroacylsilanes from trifluoroethanol
  • Trifluoroethanol as a metal-free, homogeneous and recyclable medium for the efficient one-pot synthesis of a-amino nitriles and a-amino phosphonates
  • Video For Production Process For TFE
  • Effects of trifluoroethanol as a co-solvent on the electrochemical
    oxidation of hardly oxidizable organic compounds
  • A preliminary study on microwave assisted metal-free epoxidation of cyclic olefins by hydrogen peroxide –trifluoroethanol system.


  • Debenzylation using catalytic hydrogenolysis in trifluoroethanol,
  • Electrochemical oxidation of 2,2,2-trifluoroethanol
  • Novel trifluoroethanol mediated synthesis of benzo[a]pyrene
    7,8-diol 9,10-epoxide adducts
  • Trifluoroethanol as a metal-free, homogeneous and recyclable medium for the efficient one-pot synthesis of a-amino nitriles and a-amino phosphonates
  • Practitioner’s guide to method development in thin-layer
  • Characterization of the non-native trifluoroethanol-induced
    intermediate conformational state of the Shiga toxin B-subunit
  • Trifluoroethanol may form a solvent matrix for assisted hydrophobic interactions between peptide side chains


  • Use of electrospinning technique for biomedical applications
  • The Latent Application of Ionic Liquids in Absorption Refrigeration
  • Application of the Diffusion–Collision Model to the Folding of Three-helix Bundle Proteins
  • Use Of Proteomics For The Analysis Of Hard-To-Dissect Biological Samples

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