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Salicylic acid is used to treat many skin disorders, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, common warts, and plantar warts, depending on the dosage form strength of the preparation. White, needle crystalline, water-soluble solid or syrup, C6H10O8, usually made by the oxidation of cane sugar, glucose, or starch by nitric acid. Also called Glucaric acid. Saccharic acid, also called glucaric acid, is a chemical compound with the formula C6H10O8. It is derived by oxidizing a sugar such as glucose with nitric acid. The salts of saccharic acid are called saccharates. Grapefruits were found to contain D-glucaric acid, which has anticancer properties. In the present investigation, method has develope the quantification of D-glucaric acid in grapefruit by high-performance liquid chromatography (HPLC) using a simple isocratic mobile phase with detection at 210 nm. Grapefruit samples were homogenized, centrifuged and filtered through a 0.45 macron membrane and injected into a HPLC system. The developed method was used for the quantification of D-glucaric acid in nine widely used grapefruit varieties. Furthermore, the identity of D-glucaric acid was confirmed by mass spectra. Seasonal variation of D-glucaric acid within the individual varieties were also measured in fruits harvested during November, February and May. The overall trend of D-glucaric acid level was increased from early to late season fruits. The developed method has a sensitivity of D-glucaric acid as low as 0.05 microg with an accuracy and precision 95%. This method was found to be simple, fast, accurate and reproducible. Moreover, the identity of D-glucaric acid was confirmed by mass spectra. Additionally, the labor intensity and cost of sample preparation were greatly reduced as compared to reported methods. This is the first report on quantification of D-glucaric acid in different varieties of grapefruits from three harvesting sessions. An isocratic HPLC method has been developed for the direct measurement of d-glucaric acid in human urine. Pretreatment of urine with a boronic acid gel removed many interfering substances, including l-ascorbic acid and d-glucuroic acid. This method has a detection limit of 10µM d-glucaric acid. The run-to-run precisions were 9.1% and 7.7% at urinary d-glucaric acid concentrations of 41 and 219 µmoles/g creatinine. There is now growing evidence from animal models for the possible control of different stages of the carcinogenic process by the beta-glucuronidase inhibitor D-glucaro-1,4-lactone and its precursors such as D-glucaric acid .	General D-glucaric Acid 87-73-0,guidechem Glucaric Acid Mutagenicity studies and D-glucaric acid determination in urine of workers Potential use of D-glucaric acid derivatives in cancer prevention Production of Glucaric Acid from a Synthetic Pathway in Recombinant Escherichia coli Retrobiosynthesis of D-Glucaric acid in a Metaboligally Engineered strain of Escherichia coli MSDS CAS 53701-65-8 Properties D-Saccharic Acid, Calcium Salt Showing metabocard for Glucaric acid (HMDB00663) D-Saccharic acid potassium salt D-Saccharic Acid Monopotoassium Salt Products Ligand D-glucaric acid - InchiKey Chemicals From Biomass Biorefining and biobased products Rivertop contracts with DTI on bioglucarate-based production Rivertop Renewables to Expand Green Chemical Labs & Build Semi-Works Bio Based chemical and polymer Patent Cellular Production of Glucaric acid Glucaric Acid Monoamides And Their Use To Prepare poly Sequestering Agents Carbohydrates Acid Amide Plant Fertilizers Method of Using Nitric Acid Myo-Inositol Oxygenases Process For Producing 2-Keto Production Of adipic acid and Derivatives from Carbohydrates containg Materials Report Assessment of tetrachlorodibenzo-p-dioxin exposure using a modified D-glucaric acid assay Glucaric acid tetrakis-O-(trimethylsilyl)-, bis(trimethylsilyl) ester The Glucarate Report A New Method for D-Glucaric Acid ExcretionMeasurementThat Is Suitablefor Automated Instruments Posts Tagged d-glucaric acid Urinary D-glucaric acid a marker substance for microsomal enzyme induction Values for Urinary Excretion of D-Glucaric acid Suppliers Suppliers of China Manufacturers of china Suppliers of another china Binhai Hanhong Biochemical Suppliers of china List of Suppliers Suppliers Uk Suppliers Usa Raw material suppliers D-Sacharic acid calcium salt Carbohydrates as organic Raw material D-Sacharic acid 14-Lactone Rennovia Presentation to Bio World Order the CD ROM Today	Company profiles Company from china Company another from china Company from German Company from India Company from Japan Company from Missoula Company from Usa Consultancy Consultancy from Chemical Free Parenting Consultancy from Cleantech Open in San Francisco Consultancy from Icis Green Chemistry Consultancy from Nrel Industry Growth Forum Consultancy from Calcium D-Glucarate Biological Effects of Low Level Exposure Market Biobased Chemicals East Building block for change CA D-Glucarate (Cancer Clearing: Estrogen-Lowering; Liver Detox Supplement) Global Market Report of D-Glucaric acid Renewable Chemical Company Vitalzym, Myomin and Calcium d-Glucarate Combo Pack Study Development of a method for the quantification of D-glucaric acid in different varieties of grapefruits by high-performance liquid chromatography and mass spectra Enzyme Induction In Humans Exposed To Styrene Hplc Determination of D-Glucaric Acid in Human Urine Properties and Activity Changes of Chlorogenic Acid A Semi automated Procedure for Urinary D-Glucaric Acid Using a Centrifugal Analyzer Synthesis and properties of water-resistant poly(glucaramides) Thioethers, mutagens, and D-glucaric acid in urine of operating room personnel exposed to anesthetics Urinary Excretion of D-Glucaric Acid in Porphyria Cutanea Tarda Uses Biological and Chemical Catalysis for New Monomers from Carbohydrates and Vegetable Oils Calcium-D-Glucarate Environmental and Biological Monitoring of Styrene Exposure: Urinary Excretion of D-Glucaric Acid Compared with Exposure Indices Glucarates Hyperbflirubinemia and urinary D-glucaric acid excretion in premature infants following antepartum dexamethasone treatment Autofluorescene Bronchoscopy to White Light Bronchoscopy.
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