- Dimethyl sulfate is a chemical
compound with formula (CH3O)2SO2.
- As the dimethyl ester of sulfuric
acid, its formula is often written as (CH3)2SO4 or even Me2SO4, where
CH3 or Me is methyl.
- Under standard conditions, Me2SO4
is a colorless oily liquid with a slight onion-like odour.
- Like all strong alkylating agents,
Me2SO4 is highly toxic.
- Dimethyl sulfate can be
synthesized in the laboratory by many different syntheses, the simplest
being the esterification of sulfuric acid with methanol.
- Methyl nitrite and methyl chloro
sulfonate also result in dimethyl sulfate.
- It can be made by the continuous
reaction of dimethyl ether with sulfur trioxide.
- It is also used as a solvent for
the separation of mineral oils and for the analysis of auto fluids and
as a component of polyurethane-based adhesives.
- There is some evidence to suggest
dimethyl sulphate could produce tumours following a single exposure,
although this aspect has not been systematically investigated and the
evidence is not entirely clear.
- Dimethyl sulfate is used primarily
as a methylating agent to convert compounds such as phenols, amines, and
thiols to the corresponding methyl derivatives.
- It is used in the manufacture of
methyl esters, ethers, and amines in dyes, drugs, perfumes, pesticides,
and other organic chemicals.
- It is also used as a solvent for
the separation of mineral oils and for the analysis of auto fluids and
as a component of polyurethane-based adhesives.
- Dimethyl carbonate has far lower
toxicity compared to both dimethyl sulfate and methyl iodide and can be
used to instead of dimethyl sulfate for N-methylation.
- In general the toxicity of
methylating agents is correlated with their efficiency as methyl
transfer reagents.
- Methyl transfer is typically
assumed to occur via an SN2 reaction.
- Although dimethyl sulfate is
highly effective and affordable, its toxicity has encouraged the use of
other methylating reagents.
- Dimethyl sulfate can effect the
base-specific cleavage of guanine in DNA by rupturing the imidazole
rings present in guanine.
- This process can be used to
determine base sequencing.
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Introduction
- Dimethyl-Sulfate
- Dimethyl Sulfate
-
Dimethyl sulfate
-
Diethyl
sulfate Information
Process
- Sulfuric Acid, Diethyl Ester
-
Methylation of Ribonucleic Acid by the
Carcinogens Dimethyl Sulphate, N-Methyl-N-nitrosourea and
N-Methyl-N'-nitro-N-nitrosoguanidine
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Analysis of Duplex DNA by Triple Helix
Formation
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Effect of alkylation on the secondary
structure of DNA
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Modulation of RNA Tertiary Folding by
Incorporation of Caged Nucleotides
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In Vivo Ultraviolet and
Dimethyl Sulfate Foot printing of the 5 Region of the Expressed and
Silent Xist Alleles
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Oxidation of Butyric acid with
chromic anhydride & Sulfuric acid
Product
-
Dimethyl sulfate
-
Dimethyl sulfate
Dimethyl Sulfate Product
specification
Report
-
Dimethyl Sulfate
-
Dimethyl Sulfate report
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Carcinogens In the Context of council
Directive
-
Substance Profile for the Challenge
Sulfuric acid, dimethyl ester
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Dimethyl sulfate summary
-
Tariff Legislation
Toxicity &
Safety
-
Dimethyl sulfate
-
Toxic air contaminants
-
Dimethyl carbonate for environmentally
benign reactions
-
Dimethyl sulfate Hazards
-
Dimethyl sulphate and diethyl sulphate
in air
Suppliers
-
Dimethyl sulphate Suppliers
-
Manufacturers of dimethyl
sulphate
Msds
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Diethyl sulfate, 99%
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Bile Esculin Azide Agar
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Dimethyl sulfate 99+%
-
Oligo d(T)
-
Dimethyl sulfate Msds
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Dimethyl sulfate
-
Safety data for dimethyl
sulfate |
Application
- Dimethyl Sulfate
-
Efficient use of trimethylsulfonium
methyl sulfate as a reagent for the epoxidation of carbonyl-containing
compounds
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Preparation of Sulfur Trioxide and
Oleum
Technology
-
Dimethyl Sulfate-Doped Polyaniline and
Its Electrochemical Properties as the Electrodes of Lithium Secondary
Battery and Redox Super capacitor
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Diverse ratios of mutations to
chromosome aberrations in barley treated with diethyl sulfate &
Gamma rays
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DNA Sequencing
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A review of DNA sequencing
techniques
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Trace Derivatization of cytosine with
pentafluorobenzoyl chloride & Dimethyl Sulfate
Company
Profile
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Company From China
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Company From New York
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Company From USA
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Company From China
Consultants
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Consultant from California
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Consultant from Romania
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Consultant from UK
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Consultant from USA
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Consultant from US
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Experts of Dimethyl sulfate
Patent
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Dimethyl sulfate quaternary ammonium
salt of 1-acryloyl-4-methyl piperazine
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Preparation of dimethyl sulfate
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Minimization of volatile organic
sulphur byproducts in dimethyl sulfate quaternization of amines made
with hypophorous acid
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Method of producing dimethyl phthalate
from naphthalene based chemicals
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Mutant microorganism and its use in
removing organic sulfur compounds
Raw Material
suppliers
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Methanol Wholesale Supplier
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Suppliers of Methanol
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Methanol exporters
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Methyl Nitrite suppliers
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Sulfuric acid Suppliers
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Manufacturers of Sulfuric acid
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