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- Epicatechin has
previously been suggested to rapidly reverse alloxan diabetes in
rats.
- We have assessed the
therapeutic value of the compound in two further animal models of
insulin-dependent diabetes mellitus, namely streptozotocin-diabetic
rats and the spontaneously diabetic BB/E rat.
- There was no
indication of areversal of established diabetes in either the
streptozotocin-diabetic or the spontaneously diabetic BB/E rats.
- Moreover, epicatechin
also failed to halt the progression of the disease in prediabetic
BB/E rats.
- Earlier claims of the
potential use of epicatechin as an antidiabetic agent must therefore
be treated with some caution.
- Methods have been used
that resolve stereoisomers of epicatechin and catechin. In beans
harvested from unripe and ripe cacao pods, we find only
(-)-epicatechin and (+)-catechin with (-)-epicatechin being by far
the predominant isomer.
- When beans are
fermented there is a large loss of both (-)-epicatechin and
(+)-catechin, but also the formation of (-)-catechin.
We hypothesize that the heat of fermentation may, in part, be
responsible for the formation of this enantiomer.
- When beans are
progressively roasted at conditions described as low, medium and
high roast conditions, there is a progressive loss epicatechin and
(+)-catechin and an increase in (-)-catechin with the higher roast
levels.
- When natural and
Dutch-processed cacao powders are analyzed, there is progressive
loss of both epicatechin and (+)-catechin with lesser losses of
(catechin.
- We thus observe that
in even lightly Dutch-processed powder, the level of (-)-catechin
exceeds the level of (-)-epicatechin.
- The results indicate
that much of the increase in the level of (-)-catechin observed
during various processing steps may be the result of heat-related
epimerization from (-)-epicatechin.
- Epicatechin
effects would be beneficial in supporting the management of
secondary complications of diabetes.
- Polyphenols were shown
to be useful in the long term preservation of rat pancreatic islets
in vitro under physiological conditions
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General
- Cocoa nutrient for
'lethal ills'
- Epicatechin
- Epicatechin mediates
beneficial effects of flavanol-rich cocoa
- Health Benefits of
Epicatechin
- Green tea and cocoa
epicatechin
-
Isolation and identification of procyanidins in apple
- Catechin
MSDS
-
(-)Epicatechin
205672
- Industry consensus
study on an HPLC
fluorescence method for the determination of
(±)-catechin and (±)-epicatechin in cocoa
- Investigation of
epicatechin in barberry fruits
- Epicatechin gallate
from green tea
- Simultaneous isolation
of catechin, epicatechin, rutin and apigenin from spearmint
- Supercritical Carbon
Dioxide (SC-CO ) Extraction of Catechin, Epicatechin,
- Epicatechin, 99+%
- Epicatechin
Products
- The beneficial
vascular effects of cacao flavanols
- Epicatechin ingested
via cocoa products reduces blood pressure in humans:
- Epicatechin (EC)
- Enerhealth Coco Mojo
- Epicatechin
biochemical research.
- Epicatechin
(Catechins, Tannins family)
- Epicatechin Green Tea
and Cocoa can lower Diabetes Risk
Patent
- Antiviral
eplicatechins oligomer
- Epicatechin and
vasodilation
- Food suppements
containing polyphenols
- Method and composition
for treatment of diabetes
- Preparation of
Catechin
- Process for
controlling the isomerization
- Synergistic effects of
blending multiple additives
- Synthesis of
epecatechin
- Use of epicatechin and
derivatives and salt for cardiac protection
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Newyork
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another Newyork
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Market
- Cacao benefit and side
effects, antioxidant content, health benefit
- Direct
enantioseparation of catechin and epicatechin
- Epicatechin gallate
(ECG) (CAS 1257-08-5) Market Research Report 2012
- Global Market Report
of L-Epicatechin
- L-epicatechin (CAS
490-46-0) Market Research
- Inhibition of
Proliferation of Human Cancer Cells and Cyclooxygenase Enzymes
Uses
- Antibacterial action
of several tannins against Staphylococcus aureus
- Bakauan-babae
- Epicatechin:
Endothelial Function and Blood Pressure
- Epicatechin Uses
- Epicatechin Extract
- Hawthorn:Research
Update
- Vivo Comparison
of the Bioavailability of (+)-Catechin, (−)-Epicatechin
Study
- Assessment of the
antidiabetic activity of epicatechin in streptozotocin-diabetic
-
BloodVessels/Endothelium
- Epicatechin Png
- Impact of
Fermentation, Drying, Roasting, and Dutch Processing
- Simultaneous
determination of theobromine
Technology
- Chocolate can boost
exercise endurance, says study
- HPLC determination of
the content of catechin
- Improve Nutrition and
End Childhood Obesity
- Metabolism of the
Flavonoid Epicatechin
- Procyanidins from
Adansonia digitata.
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